Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 13/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24389531 | 0.82 | VNN1 (0.57) | VNN1PTGS1KCNH2RAB9ANPC1 | |
| SCHEMBL574239 | 0.82 | VNN1 (0.63) | VNN1KMT2AHPGDMEN1 | |
| SCHEMBL16685028 | 0.81 | PTGS1 (0.52) | VNN1PTGS1KCNH2 | |
| SCHEMBL19832435 | 0.81 | PTGS1 (0.52) | VNN1PTGS1KCNH2 | |
| Pantethine SCHEMBL1650348 | 0.79 | PTGS1 (0.56) | VNN1PTGS1KCNH2 | |
| Pantethine SCHEMBL59597 | 0.79 | PTGS1 (0.56) | VNN1PTGS1KCNH2 | |
| Pantethine SCHEMBL19544641 | 0.79 | PTGS1 (0.56) | VNN1PTGS1KCNH2 | |
| SCHEMBL21996172 | 0.79 | PTGS1 (0.51) | VNN1PTGS1KCNH2 | |
| SCHEMBL21996248 | 0.79 | PTGS1 (0.54) | VNN1PTGS1KCNH2KMT2AMEN1 | |
| SCHEMBL21996249 | 0.79 | PTGS1 (0.54) | VNN1PTGS1KCNH2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012017400-A1 | SYNTHESIS OF ACYL-PANTETHEINE DERIVATIVES AND THE USE THEREOF IN THE SYNTHESIS OF ACYL-COENZYME A DERIVATIVES | NORTH-WEST UNIVERSITY (ZA) | 2012-02-09 | — | — | WO | disclosed |
| US-5990094-A | SEROTONIN N-ACETYLTRANSFERASE INHIBITORS WHICH CAN SERVE AS BIOLOGICAL TOOLS THAT HELP REVEAL BIOLOGICAL FUNCTIONS FOR MELATONIN AND PINEAL SEROTONIN IN VIVO; ACETYL-COA N-ACETYL TRYPTAMINE DERIVATIVES OF GIVEN STRUCTURE | THE ROCKEFELLER UNIVERSITY (US) | 1999-11-23 | — | — | US | disclosed |