SCHEMBL574239

SCHEMBL574239

CC(C)(CO)C(O)C(=O)NCCC(=O)NCCSCc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
VNN1 O95497 12/20 0.63
ALDH1A1 P00352 6/20 0.54
HPGD P15428 5/20 0.54
KMT2A Q03164 3/20 0.49
MEN1 O00255 2/20 0.49
LMNA P02545 2/20 0.49
KDM4E B2RXH2 1/20 0.49
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11191170 0.93 VNN1 (0.64) VNN1ALDH1A1HPGDKMT2ALMNA
Pantothenic Acid, Racemic SCHEMBL11196558 0.85 VNN1 (0.60) VNN1CYP2C19
SCHEMBL24389531 0.82 VNN1 (0.57) VNN1HPGDSMN1; SMN2
SCHEMBL574067 0.82 VNN1 (0.57) VNN1HPGDKMT2AMEN1
SCHEMBL15750065 0.82 ALDH1A1 (0.47) VNN1ALDH1A1HPGDKMT2AMEN1
SCHEMBL17742186 0.81 VNN1 (0.67) VNN1HPGDKMT2AMEN1LMNA
SCHEMBL15750036 0.80 ALDH1A1 (0.42) VNN1ALDH1A1HPGDKMT2AMEN1
Pantethine SCHEMBL59597 0.79 PTGS1 (0.56) VNN1ALDH1A1
Pantethine SCHEMBL1650348 0.79 PTGS1 (0.56) VNN1ALDH1A1
Pantethine SCHEMBL19544641 0.79 PTGS1 (0.56) VNN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012017400-A1 SYNTHESIS OF ACYL-PANTETHEINE DERIVATIVES AND THE USE THEREOF IN THE SYNTHESIS OF ACYL-COENZYME A DERIVATIVES NORTH-WEST UNIVERSITY (ZA) 2012-02-09 WO disclosed