Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.64 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.64 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.64 |
| ▸ | AR | P10275 | 10/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | GHSR | Q92847 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5743170 | 0.89 | NR3C1 (0.65) | PGRNR3C1NR3C2ARCYP2C19 | |
| SCHEMBL4617201 | 0.85 | NR3C1 (0.71) | PGRNR3C1NR3C2AR | |
| SCHEMBL5740910 | 0.84 | NR3C1 (0.65) | PGRNR3C1NR3C2AR | |
| SCHEMBL5742025 | 0.82 | NR3C1 (0.68) | PGRNR3C1NR3C2AR | |
| SCHEMBL5744371 | 0.82 | NR3C1 (0.68) | PGRNR3C1NR3C2AR | |
| SCHEMBL5742909 | 0.81 | NR3C1 (0.66) | PGRNR3C1NR3C2AR | |
| SCHEMBL13088032 | 0.79 | AR (0.57) | PGRARCYP2C19ABCB11ALB | |
| SCHEMBL292961 | 0.78 | PGR (1.00) | PGRNR3C1NR3C2 | |
| SCHEMBL10062544 | 0.78 | AR (0.72) | PGRARCYP2C19ABCB11ALB | |
| SCHEMBL13996877 | 0.77 | AR (0.71) | PGRARCYP2C19ABCB11ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1467982-B1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL FORMULATIONS CONTAINING THEM, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMA (US) | 2006-11-22 | — | — | EP | claimed |
| US-7189758-B2 | Glucocorticoid mimetics, methods of making them, pharmaceutical formulations, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2007-03-13 | — | — | US | disclosed |
| US-7189758-B2 | Glucocorticoid mimetics, methods of making them, pharmaceutical formulations, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2007-03-13 | — | — | US | disclosed |
| US-6960581-B2 | Glucocorticoid mimetics, methods of making them, pharmaceutical formulations, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-11-01 | — | — | US | disclosed |