Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 5/20 | 0.68 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.68 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.68 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.68 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.68 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.68 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.68 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.68 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.68 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.62 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31307068 | 0.88 | HDAC3 (0.64) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL69679 | 0.84 | HDAC3 (0.69) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL1779820 | 0.84 | HDAC3 (0.74) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL10592503 | 0.80 | SIRT2 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL12430571 | 0.80 | HDAC3 (0.73) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11234991 | 0.80 | SIRT2 (0.58) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL69680 | 0.80 | HDAC3 (0.63) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8641265 | 0.79 | SIRT2 (0.68) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL13604182 | 0.79 | HDAC3 (1.00) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7413562 | 0.79 | HDAC3 (0.71) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1381663-B1 | CLEANING COMPOSITIONS | ESC INC (US) | 2006-06-14 | — | — | EP | disclosed |
| US-6851432-B2 | Aqueous cleaning composition comprising an alkanolamine, a tetraalkylammonium hydroxide, nonmetallic fluoride salt, a corrosion inhibitor, e.g. ascorbic acid or its derivatives alone or in combination, balance water for removal of | ADVANCED TECHNOLOGY MATERIALS, INC. (US) | 2005-02-08 | — | — | US | disclosed |
| EP-1381663-A1 | CLEANING COMPOSITIONS | ESC Inc. (US) | 2004-01-21 | — | — | EP | disclosed |
| US-20030207777-A1 | Cleaning compositions | MORGAN STANLEY SENIOR FUNDING, INC. | 2003-11-06 | — | — | US | disclosed |
| US-6627587-B2 | Mixture of alkanolamine, tetraalktlammonium hydroxide, fluoride compound and corrosion inhbitor | ESC INC. | 2003-09-30 | — | — | US | disclosed |
| US-20030017962-A1 | Cleaning compositions | ESC, INC | 2003-01-23 | — | — | US | disclosed |
| WO-2002086045-A1 | CLEANING COMPOSITIONS | ESC, INC. (US) | 2002-10-31 | — | — | WO | disclosed |