Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4390254 | 0.83 | TSHR (0.42) | LMNASMN1; SMN2HTTTDP1TSHR | |
| SCHEMBL5486291 | 0.82 | ALDH1A1 (0.39) | LMNASMN1; SMN2HTTALDH1A1RECQL | |
| SCHEMBL2298630 | 0.80 | TSHR (0.39) | LMNASMN1; SMN2HTTTDP1TSHR | |
| SCHEMBL10914343 | 0.80 | TSHR (0.39) | LMNASMN1; SMN2TDP1TSHRALDH1A1 | |
| SCHEMBL10914346 | 0.80 | TSHR (0.39) | LMNASMN1; SMN2TDP1TSHRALDH1A1 | |
| SCHEMBL28850127 | 0.76 | TSHR (0.42) | LMNASMN1; SMN2TDP1TSHRALDH1A1 | |
| SCHEMBL2685223 | 0.73 | HTT (0.47) | LMNASMN1; SMN2HTTTDP1TSHR | |
| SCHEMBL4527774 | 0.72 | CYP19A1 (0.43) | LMNASMN1; SMN2HTTTDP1TSHR | |
| SCHEMBL11208136 | 0.70 | TSHR (0.53) | LMNASMN1; SMN2HTTTDP1TSHR | |
| SCHEMBL30780978 | 0.70 | TSHR (0.53) | LMNASMN1; SMN2HTTTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1340753-B1 | CARBAMATE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2006-01-11 | — | — | EP | disclosed |