Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 0.67 |
| ▸ | PGR | P06401 | 4/20 | 0.67 |
| ▸ | NR3C2 | P08235 | 11/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4617886 | 0.91 | NR3C1 (0.72) | NR3C1PGRNR3C2 | |
| SCHEMBL5742903 | 0.91 | NR3C1 (0.69) | NR3C1PGRNR3C2 | |
| SCHEMBL5742197 | 0.91 | NR3C1 (0.69) | NR3C1PGRNR3C2 | |
| SCHEMBL5741213 | 0.88 | NR3C1 (0.66) | NR3C1PGRNR3C2 | |
| SCHEMBL5742909 | 0.88 | NR3C1 (0.66) | NR3C1PGRNR3C2 | |
| SCHEMBL3657125 | 0.83 | NR3C1 (0.71) | NR3C1PGRNR3C2 | |
| SCHEMBL5743170 | 0.82 | NR3C1 (0.65) | NR3C1PGRNR3C2 | |
| SCHEMBL5740864 | 0.81 | NR3C1 (0.54) | NR3C1PGRNR3C2 | |
| SCHEMBL291648 | 0.81 | PGR (1.00) | NR3C1PGRNR3C2 | |
| SCHEMBL450448 | 0.79 | NR3C1 (0.82) | NR3C1PGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1467982-B1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL FORMULATIONS CONTAINING THEM, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMA (US) | 2006-11-22 | — | — | EP | claimed |
| US-6960581-B2 | Glucocorticoid mimetics, methods of making them, pharmaceutical formulations, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-11-01 | — | — | US | disclosed |