Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5742837 | 0.92 | HRH4 (0.50) | HRH4HRH3USP2LMNATSHR | |
| Hydrochloric Acid SCHEMBL5742635 | 0.91 | HRH4 (0.49) | HRH4HRH3USP2LMNATSHR | |
| SCHEMBL5744463 | 0.84 | HRH4 (0.45) | HRH4HRH3LMNATSHRHTT | |
| SCHEMBL17979678 | 0.81 | NUDT1 (0.55) | HRH4HRH3ARPRCPOPRK1 | |
| SCHEMBL17979720 | 0.81 | NUDT1 (0.55) | HRH4HRH3ARPRCPOPRK1 | |
| SCHEMBL17979675 | 0.81 | NUDT1 (0.55) | HRH4HRH3ARPRCPOPRK1 | |
| SCHEMBL5741135 | 0.79 | MAPT (0.61) | HRH4HRH3USP2LMNATSHR | |
| SCHEMBL17979756 | 0.77 | NUDT1 (0.57) | HRH4HRH3USP2LMNATSHR | |
| SCHEMBL17979726 | 0.77 | NUDT1 (0.57) | HRH4HRH3USP2LMNATSHR | |
| SCHEMBL17979727 | 0.77 | NUDT1 (0.57) | HRH4HRH3USP2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654249-A1 | ANTHELMINTIC AND INSECTICIDE PYRIMIDINE DERIVATIVES | Pharmacia & Upjohn Company LLC (US) | 2006-05-10 | — | — | EP | claimed |
| WO-2005014573-A1 | ANTHELMINTIC AND INSECTICIDE PYRIMIDINE DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-02-17 | — | — | WO | claimed |
| US-20050032810-A1 | Novel anthelmintic and insecticidal compositions | PHARMACIA AND UPJOHN COMPANY | 2005-02-10 | — | — | US | claimed |
| EP-1654249-A1 | ANTHELMINTIC AND INSECTICIDE PYRIMIDINE DERIVATIVES | Pharmacia & Upjohn Company LLC (US) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005014573-A1 | ANTHELMINTIC AND INSECTICIDE PYRIMIDINE DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-02-17 | — | — | WO | disclosed |
| US-20050032810-A1 | Novel anthelmintic and insecticidal compositions | PHARMACIA AND UPJOHN COMPANY | 2005-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032810-A1 | Novel anthelmintic and insecticidal compositions | ACHE, DHX29, DHX35 | HRH4 172/4885HRH3 153/4885AR 4860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.