SCHEMBL57432

SCHEMBL57432

CC(C)(C)OC(=O)N[C@H](C(=O)O)C(C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.50
CA1 P00915 1/20 0.50
CA7 P43166 1/20 0.50
CTSK P43235 9/20 0.46
CTSS P25774 6/20 0.46
CYP2D6 P10635 1/20 0.45
MEN1 O00255 1/20 0.44
GAA P10253 1/20 0.44
KMT2A Q03164 1/20 0.44
CTSL P07711 1/20 0.41
CTSB P07858 1/20 0.41
TSHR P16473 1/20 0.39
HSD17B10 Q99714 1/20 0.39
PPARA Q07869 2/20 0.38
PPARG P37231 1/20 0.38
ATM Q13315 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL83699 1.00 CA2 (0.50) CA2CA1CA7CTSKCTSS
SCHEMBL90052 1.00 CA2 (0.50) CA2CA1CA7CTSKCTSS
SCHEMBL464290 0.93 CTSK (0.45) CA2CA1CA7CTSKCTSS
SCHEMBL30673406 0.86 CA1 (0.46) CA2CA1CA7CTSKCTSS
SCHEMBL206502 0.86 CA1 (0.44) CA2CA1CA7CTSKCTSS
SCHEMBL873787 0.86 CA1 (0.44) CA2CA1CA7CTSKCTSS
SCHEMBL873398 0.86 CA1 (0.44) CA2CA1CA7CTSKCTSS
SCHEMBL23722683 0.84 CA1 (0.43) CA2CA1CA7CTSKCTSS
SCHEMBL3805811 0.84 CTSK (0.44) CA2CA1CA7CTSKCTSS
SCHEMBL21746358 0.84 CA1 (0.43) CA2CA1CA7CTSKCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1798 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115873034-B Semi-active phosphoramide ligand and preparation method thereof 上海毕臣生化科技有限公司 2025-06-24 CN claimed
CN-117624280-B GATA transcription factor protein degradation targeting complex compound, and preparation method and application thereof 斯达时代药业(苏州)有限公司 2025-02-25 CN claimed
CN-117624280-A GATA transcription factor protein degradation targeting complex compound, and preparation method and application thereof 南京师范大学 2024-03-01 CN claimed
CN-114907231-B Indene chiral spiro fluorescent compound, and preparation method and application thereof 杭州师范大学 2024-02-23 CN claimed
CN-117186004-A Synthesis method of axial chiral biaryl quinoline nitroxide compound 河南师范大学 2023-12-08 CN claimed
CN-116874803-A Antibacterial dendritic polyester polymer and preparation method and application thereof 清华大学深圳国际研究生院 2023-10-13 CN claimed
CN-115873034-A Semi-active phosphamide ligand and preparation method thereof 上海毕臣生化科技有限公司 2023-03-31 CN claimed
CN-115611881-A Method for synthesizing novel VHL ligand 4-F-VH032 复旦大学 2023-01-17 CN claimed
CN-115385984-A Peptide-like derivative, preparation method and application 北京科翔中升医药科技有限公司 2022-11-25 CN claimed
CN-115108937-A Synthesis method of alpha-azidoketone containing three-level stereocenter 常州大学 2022-09-27 CN claimed
CN-114907231-A Indene chiral spiro fluorescent compound and preparation method and application thereof 杭州师范大学 2022-08-16 CN claimed
CN-114478627-A Allylation monophosphine ligand and preparation method thereof 湖北大学 2022-05-13 CN claimed
EP-2423187-A1 PROCESS FOR PRODUCTION OF N-ALKOXYCARBONYL-tert-LEUCINES Kaneka Corporation (JP) 2012-02-29 EP claimed
US-20260144788-A1 COMPOUND FOR SHP2 PROTEIN DEGRADATION AND MEDICAL USES THEREOF UBIX THERAPEUTICS, INC. (KR) 2026-05-28 US disclosed
CN-122059930-A Cdc25 phosphatase degradation agent based on quinoline dione skeleton, and preparation method and application thereof 山东大学 2026-05-19 CN disclosed
US-12624044-B2 SMARCA degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2026-05-12 US disclosed
EP-0615969-A1 2,4-Diamino-3-hydroxycarboxylic acid derivatives SANDOZ LTD. (CH) 1994-09-21 EP disclosed
US-5338726-A Hypotensive agents, antiulcer agents ABBOTT LABORATORIES (US) 1994-08-16 US disclosed
WO-1993020099-A2 CCK AND/OR GASTRIN RECEPTOR LIGANDS FERRING B.V. (NL) 1993-10-14 WO disclosed
WO-1992013545-A1 ENDOTHELIN CONVERTING ENZYME INHIBITORS ABBOTT LABORATORIES (US) 1992-08-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144788-A1 COMPOUND FOR SHP2 PROTEIN DEGRADATION AND MEDICAL USES THEREOF PTPN6, PTPN1, PTPN11 CA2 634/4885CA1 1860/4885CA7 825/4885
US-12624044-B2 SMARCA degraders and uses thereof SMARCA1, SMARCC1, SMARCA2 CA2 2413/4885CA1 2045/4885CA7 3020/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.