SCHEMBL90052

SCHEMBL90052

CC(C)(C)OC(=O)NC(C(=O)O)C(C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.50
CA1 P00915 1/20 0.50
CA7 P43166 1/20 0.50
CTSK P43235 9/20 0.46
CTSS P25774 6/20 0.46
CYP2D6 P10635 1/20 0.45
MEN1 O00255 1/20 0.44
GAA P10253 1/20 0.44
KMT2A Q03164 1/20 0.44
CTSL P07711 1/20 0.41
CTSB P07858 1/20 0.41
TSHR P16473 1/20 0.39
HSD17B10 Q99714 1/20 0.39
PPARA Q07869 2/20 0.38
PPARG P37231 1/20 0.38
ATM Q13315 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL57432 1.00 CA2 (0.50) CA2CA1CA7CTSKCTSS
SCHEMBL83699 1.00 CA2 (0.50) CA2CA1CA7CTSKCTSS
SCHEMBL464290 0.93 CTSK (0.45) CA2CA1CA7CTSKCTSS
SCHEMBL30673406 0.86 CA1 (0.46) CA2CA1CA7CTSKCTSS
SCHEMBL206502 0.86 CA1 (0.44) CA2CA1CA7CTSKCTSS
SCHEMBL873787 0.86 CA1 (0.44) CA2CA1CA7CTSKCTSS
SCHEMBL873398 0.86 CA1 (0.44) CA2CA1CA7CTSKCTSS
SCHEMBL23722683 0.84 CA1 (0.43) CA2CA1CA7CTSKCTSS
SCHEMBL3805811 0.84 CTSK (0.44) CA2CA1CA7CTSKCTSS
SCHEMBL21746358 0.84 CA1 (0.43) CA2CA1CA7CTSKCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 810 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024017221-A1 SYNTHESIS METHOD FOR α-AZIDO KETONE CONTAINING TERTIARY STEREOCENTER 常州大学 2024-01-25 WO claimed
CN-115108937-B Synthesis method of alpha-azido ketone containing three-level stereo center 常州大学 2023-08-22 CN claimed
CN-115611881-A Method for synthesizing novel VHL ligand 4-F-VH032 复旦大学 2023-01-17 CN claimed
US-20260144788-A1 COMPOUND FOR SHP2 PROTEIN DEGRADATION AND MEDICAL USES THEREOF UBIX THERAPEUTICS, INC. (KR) 2026-05-28 US disclosed
US-12624044-B2 SMARCA degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2026-05-12 US disclosed
US-20260125421-A1 ANTIVIRAL COMPOUNDS HOFFMANN-LA ROCHE INC. (US) 2026-05-07 US disclosed
US-20260115296-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF RAPIDLY ACCELERATED FIBROSARCOMA POLYPEPTIDES UNIV YALE (US) 2026-04-30 US disclosed
WO-2026090317-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. (US) 2026-04-30 WO disclosed
US-20260109672-A1 SARS-COV-2 MPRO INHIBITORS AND USES THEREOF NXERA PHARMA UK LIMITED (GB) 2026-04-23 US disclosed
EP-3886904-B1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-04-22 EP disclosed
EP-4720058-A2 BIFUNCTIONAL DEGRADERS AND USES THEREOF Casma Therapeutics, Inc. (US) 2026-04-08 EP disclosed
WO-2001009096-A2 POTASSIUM CHANNEL OPENERS ABBOTT LABORATORIES (US) 2001-02-08 WO disclosed
EP-1047665-A1 MATRIX METALLOPROTEASE INHIBITORS Pfizer Limited (GB) 2000-11-02 EP disclosed
WO-2000061134-A1 ANTIMICROBIAL AGENTS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 2000-10-19 WO disclosed
WO-1999035124-A1 MATRIX METALLOPROTEASE INHIBITORS PFIZER LIMITED (GB) 1999-07-15 WO disclosed
US-5338726-A Hypotensive agents, antiulcer agents ABBOTT LABORATORIES (US) 1994-08-16 US disclosed
US-5304549-A Control or prevention of degenerative joint diseases HOFFMANN-LA ROCHE INC. (US) 1994-04-19 US disclosed
WO-1993001166-A1 4-AMINO-3-HYDROXYCARBOXYLIC ACID DERIVATIVES SANDOZ LTD. (CH) 1993-01-21 WO disclosed
WO-1992013545-A1 ENDOTHELIN CONVERTING ENZYME INHIBITORS ABBOTT LABORATORIES (US) 1992-08-20 WO disclosed
EP-0497192-A2 Amino acid derivatives F. HOFFMANN-LA ROCHE AG (CH) 1992-08-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144788-A1 COMPOUND FOR SHP2 PROTEIN DEGRADATION AND MEDICAL USES THEREOF PTPN6, PTPN1, PTPN11 CA2 634/4885CA1 1860/4885CA7 825/4885
US-20260109672-A1 SARS-COV-2 MPRO INHIBITORS AND USES THEREOF ACE2, ACE, TMPRSS2 CA2 351/4885CA1 2298/4885CA7 302/4885
US-20260125421-A1 ANTIVIRAL COMPOUNDS ZC3HAV1, ZC3HAV1L, GTF3C3 CA2 934/4885CA1 1307/4885CA7 338/4885
US-12624044-B2 SMARCA degraders and uses thereof SMARCA1, SMARCC1, SMARCA2 CA2 2413/4885CA1 2045/4885CA7 3020/4885
US-20260115296-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF RAPIDLY ACCELERATED FIBROSARCOMA POLYPEPTIDES CRBN, VHL, ADRM1 CA2 3749/4885CA1 3147/4885CA7 3803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.