SCHEMBL5743452

SCHEMBL5743452

COc1ncc(S(=O)(=O)O)c(OC)n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NAMPT P43490 1/20 0.41
▸ KDM4E B2RXH2 1/20 0.40
▸ PKM P14618 1/20 0.40
▸ PLAU P00749 1/20 0.36
▸ PTGES2 Q9H7Z7 1/20 0.36
▸ CYP1A2 P05177 4/20 0.35
▸ QPCT Q16769 1/20 0.35
▸ QPCTL Q9NXS2 1/20 0.35
▸ CRHR1 P34998 1/20 0.35
▸ LDHA P00338 1/20 0.34
▸ ACACB O00763 2/20 0.33
▸ PIK3CD O00329 1/20 0.33
▸ ABL1 P00519 1/20 0.33
▸ EGFR P00533 1/20 0.33
▸ HCK P08631 1/20 0.33
▸ SRC P12931 1/20 0.33
▸ PIK3CA P42336 1/20 0.33
▸ PIK3CB P42338 1/20 0.33
▸ MTOR P42345 1/20 0.33
▸ PIK3CG P48736 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28480662 0.98 NAMPT (0.40) NAMPTKDM4EPKMPLAUPTGES2
SCHEMBL28946855 0.82 PTGES2 (0.46) NAMPTKDM4EPKMPLAUPTGES2
SCHEMBL31616322 0.82 KDM4E (0.40) NAMPTKDM4EPKMPLAUPTGES2
SCHEMBL5743429 0.76 KMT2A (0.39) KDM4ECYP1A2CCR4MEN1ALDH1A1
SCHEMBL30961275 0.75 FTO (0.40) NAMPTPLAUPTGES2CYP1A2QPCT
SCHEMBL6134913 0.72 SMN1; SMN2 (0.39) KDM4EPKMCCR4
SCHEMBL9906411 0.69 GAA (0.39) KDM4EPLAUPTGES2CYP1A2QPCT
SCHEMBL2745323 0.69 TDP1 (0.51) KDM4EPLAUCYP1A2QPCTQPCTL
SCHEMBL3816071 0.69 KMT2A (0.52) PLAUCYP1A2QPCTQPCTLCRHR1
SCHEMBL8888 0.69 QPCT (0.40) PLAUCYP1A2QPCTQPCTLCRHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117660242-A Bacillus thuringiensis strain for degrading sulfonamide antibiotics and application thereof 生态环境部华南环境科学研究所(生态环境部生态环境应急研究所) 2024-03-08 — — CN claimed
CN-117645957-A Pseudomonas stutzeri strain for degrading sulfonamide antibiotics and application thereof 生态环境部华南环境科学研究所(生态环境部生态环境应急研究所) 2024-03-05 — — CN claimed
CN-117092266-A Method for detecting sulfonamide veterinary drug residue mixed solution sample in methanol 青岛博栋检测服务有限公司 2023-11-21 — — CN claimed
CN-115902023-A Method for detecting sulfonamide residues in pasture through liquid chromatography-mass spectrometry 江西省农业科学院农产品质量安全与标准研究所 2023-04-04 — — CN claimed
CN-113030308-B Detection method of sulfonamide antibiotics in biogas slurry and sample treatment method thereof 浙江省农业科学院 2022-10-28 — — CN claimed
CN-113390989-A Detection method of veterinary drug residues in fish 成都市食品药品检验研究院 2021-09-14 — — CN claimed
CN-109557206-B Method for simultaneously and accurately detecting 45 antibiotics in livestock and poultry manure 农业农村部环境保护科研监测所 2021-08-10 — — CN claimed
CN-110702805-B UPLC-MSMS detection method for establishing 19 sulfanilamide residues in cultured fish based on ASE method of C18 舟山市食品药品检验检测研究院 2021-07-02 — — CN claimed
CN-107490649-B Method for screening 62 antibacterial drugs in livestock and poultry excrement 河南省兽药饲料监察所 2020-05-12 — — CN claimed
CN-110849990-A Method for detecting veterinary drug residues in animal-derived food and application thereof 中国肉类食品综合研究中心 2020-02-28 — — CN claimed
EP-1385840-B1 SULFONAMIDES SMITHKLINE BEECHAM CORP (US) 2006-10-04 — — EP claimed
US-7091204-B2 Sulfonamides SMITHKLINE BEECHAM CORPORATION (US) 2006-08-15 — — US claimed
EP-1385840-A4 SULFONAMIDES SMITHKLINE BEECHAM CORP (US) 2005-11-23 — — EP claimed
US-20040152891-A1 Sulfonamides SMITHKLINE BEECHAM CORPORATION 2004-08-05 — — US claimed
EP-1385840-A1 SULFONAMIDES SMITHKLINE BEECHAM CORPORATION (US) 2004-02-04 — — EP claimed
WO-2002090348-A1 SULFONAMIDES SMITHKLINE BEECHAM CORPORATION (US) 2002-11-14 — — WO claimed
CN-118209718-A Method and system for simultaneously detecting residues of sulfonamides, tetracyclines and quinolones 上海雄图生物科技有限公司 2024-06-18 — — CN disclosed
CN-117645957-B Pseudomonas stutzeri strain for degrading sulfonamide antibiotics and application thereof 生态环境部华南环境科学研究所(生态环境部生态环境应急研究所) 2024-04-30 — — CN disclosed
WO-2002090348-A1 SULFONAMIDES SMITHKLINE BEECHAM CORPORATION (US) 2002-11-14 — — WO disclosed
CN-1354740-A Pharmaceutical compounds NICOX SA (FR) 2002-06-19 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040152891-A1 Sulfonamides UTS2R, PRSS2, STS NAMPT 291/4885KDM4E 3916/4885PKM 4216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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