SCHEMBL5743643

SCHEMBL5743643

CS(=O)(=O)OC1CN(C(c2ccccc2)(c2ccccc2)c2ccccc2)C1

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.37
PIM3 Q86V86 1/20 0.37
CHRM3 P20309 11/20 0.35
CHRM2 P08172 3/20 0.35
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
CYP2D6 P10635 1/20 0.34
TSHR P16473 1/20 0.34
PMP22 Q01453 1/20 0.34
KMT2A Q03164 1/20 0.34
SLC6A2 P23975 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5743233 0.88 CHRM3 (0.40) CHRM3CHRM2
SCHEMBL5743611 0.86 CYP2D6 (0.39) CHRM3CYP2D6L3MBTL1
SCHEMBL5743658 0.84 CHRM3 (0.40) CHRM3CHRM2MEN1LMNACYP2D6
SCHEMBL5745637 0.83 L3MBTL1 (0.34) PIM1PIM3CHRM3CYP2D6L3MBTL1
SCHEMBL5746294 0.80 CYP2D6 (0.47) MEN1LMNACYP2D6KMT2A
SCHEMBL5743640 0.79 CYP2D6 (0.41) CHRM3CHRM2MEN1LMNACYP2D6
SCHEMBL5746067 0.79 CHRM3 (0.33) PIM1PIM3CHRM3CHRM2L3MBTL1
SCHEMBL30214804 0.78 L3MBTL1 (0.39) PIM1PIM3CHRM3CHRM2MEN1
SCHEMBL5743623 0.77 L3MBTL1 (0.33) PIM1PIM3CHRM3CHRM2CYP2D6
SCHEMBL5744733 0.76 CHRM3 (0.33) CHRM3CHRM2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1288198-B1 PROCESS FOR THE PRODUCTION OF SULFONIC ESTERS KANEKA CORP (JP) 2006-12-20 EP disclosed
US-6992205-B2 Process for the production of sulfonic esters KANEKA CORPORATION (JP) 2006-01-31 US disclosed
US-6864372-B2 Process for the production of sulfonic esters KANEKA CORPORATION (JP) 2005-03-08 US disclosed
US-6794519-B2 Process for the production of sulfonic esters KANEKA CORPORATION (JP) 2004-09-21 US disclosed
US-20030176713-A1 Reacting an amino alcohol derivative with organic sulfonyl halide in a mixed solvent composed of an aprotic organic solvent and water in presence of a non-water prohibiting inorganic base KANEKA CORPORATION (JP) 2003-09-18 US disclosed
US-20030176711-A1 Process for the production of sulfonic esters KANEKA CORPORATION (JP) 2003-09-18 US disclosed
US-20030162966-A1 PROCESS FOR THE PRODUCTION OF SULFONIC ESTERS KANEKA CORPORATION (JP) 2003-08-28 US disclosed
EP-1288198-A1 PROCESS FOR THE PRODUCTION OF SULFONIC ESTERS KANEKA CORPORATION (JP) 2003-03-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030162966-A1 PROCESS FOR THE PRODUCTION OF SULFONIC ESTERS TST, STS, SELENOI PIM1 516/4885PIM3 759/4885CHRM3 3840/4885
US-20030176711-A1 Process for the production of sulfonic esters TST, STS, SELENOI PIM1 516/4885PIM3 759/4885CHRM3 3840/4885
US-20030176713-A1 Reacting an amino alcohol derivative with organic sulfonyl halide in a mixed solvent composed of an aprotic organic solvent and water in presence of a non-water prohibiting inorganic base BRAF, ADH1C, TST PIM1 493/4885PIM3 769/4885CHRM3 3010/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.