Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 2/20 | 0.50 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4945279 | 1.00 | OXTR (0.50) | OXTRAVPR1APOLBLMNAHPGD | |
| SCHEMBL5479504 | 0.83 | OXTR (0.43) | OXTRAVPR1APOLBLMNAPKM | |
| SCHEMBL4943696 | 0.82 | OXTR (0.72) | OXTRAVPR1APOLBLMNAHPGD | |
| SCHEMBL4945363 | 0.81 | LMNA (0.52) | OXTRAVPR1APOLBLMNAHPGD | |
| SCHEMBL4940121 | 0.80 | OXTR (0.67) | OXTRAVPR1APOLBLMNAKMT2A | |
| SCHEMBL4940128 | 0.80 | OXTR (0.67) | OXTRAVPR1APOLBLMNAKMT2A | |
| SCHEMBL4938283 | 0.79 | ALDH1A1 (0.46) | OXTRPOLBMAPTMEN1KMT2A | |
| SCHEMBL7219644 | 0.79 | ALDH1A1 (0.46) | OXTRPOLBMAPTMEN1KMT2A | |
| SCHEMBL4942737 | 0.75 | ALDH1A1 (0.47) | POLBLMNAHPGDMAPTTP53 | |
| SCHEMBL4939785 | 0.74 | OXTR (0.44) | OXTRAVPR1APOLBLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268419-B1 | PYRROLIDINE DERIVATIVES USEFUL AS BAX INHIBITORS | APPLIED RESEARCH SYSTEMS (AN) | 2006-06-21 | — | — | EP | claimed |