Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 4/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | CTSG | P08311 | 2/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.39 |
| ▸ | CMA1 | P23946 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5168028 | 0.89 | PGR (0.52) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL23238 | 0.89 | PGR (0.52) | PGRADRA2AADRA2BHTR2AHRH1 | |
| Benzene SCHEMBL28162079 | 0.88 | PGR (0.50) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL7609030 | 0.87 | SRC (0.42) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL28068384 | 0.87 | SMN1; SMN2 (0.42) | PGRADRA2AADRA2BHTR2AHRH1 | |
| Acetic Acid SCHEMBL27715708 | 0.86 | PGR (0.49) | PGRADRA2AADRA2BHTR2AHRH1 | |
| Benzil SCHEMBL10413820 | 0.84 | CES2 (0.52) | PGRADRA2AADRA2BHTR2AHRH1 | |
| Benzophenone SCHEMBL9682804 | 0.84 | ALDH1A1 (0.52) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL10943759 | 0.83 | ELANE (0.51) | PGRADRA2AADRA2BHTR2AHRH1 | |
| Acetophenone SCHEMBL27577117 | 0.83 | PGR (0.46) | PGRADRA2AADRA2BHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9453950-B2 | Photochromic coating process | CARL ZEISS VISION AUSTRALIA HOLDINGS LTD. (AU) | 2016-09-27 | — | — | US | disclosed |
| US-8128990-B2 | Comprised of rigid multifunctional monomer and flexible difunctional monomers; photopolymerization of such as polyethylene glycol diacrylate, hexanediol diacrylate, methacrylated colloidal silica and pentaerythritol tetraacrylate; ophthalmic and camera lens, windows | CARL ZEISS VISION AUSTRALIA HOLDINGS LTD. (AU) | 2012-03-06 | — | — | US | disclosed |
| US-20120037859-A1 | Photochromic Coating Process | CARL ZEISS VISION AUSTRALIA HOLDINGS LTD. (AU) | 2012-02-16 | — | — | US | disclosed |
| US-8003022-B2 | Method of forming a coated optical element | CARL ZEISS VISION AUSTRALIA HOLDINGS LIMITED (AU) | 2011-08-23 | — | — | US | disclosed |
| EP-1453920-B1 | ABRASION RESISTANT COATING COMPOSITION | CARL ZEISS VISION AU HOLDING (AU) | 2011-04-13 | — | — | EP | disclosed |
| US-20090026638-A1 | METHOD OF FORMING A COATED OPTICAL ELEMENT | CARL ZEISS VISION AUSTRALIA HOLDINGS LIMITED (AU) | 2009-01-29 | — | — | US | disclosed |
| EP-1453662-B1 | PHOTOCHROMIC COATING PROCESS | CARL ZEISS VISION AU HOLDING (AU) | 2008-10-01 | — | — | EP | disclosed |
| US-20050171231-A1 | Abrasion resistant coating composition | CARL ZEISS VISION AUSTRALIA HOLDINGS LTD. (AU) | 2005-08-04 | — | — | US | disclosed |
| US-20050116381-A1 | Photochromic coating process | SOLA INTERNATIONAL HOLDINGS LIMITED | 2005-06-02 | — | — | US | disclosed |
| US-4921908-A | HYDROGELS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-05-01 | — | — | US | disclosed |
| US-4758448-A | Coated ophthalmic lenses and method for coating the same | SIGNET ARMORLITE, INC. (US) | 1988-07-19 | — | — | US | disclosed |
| US-4693939-A | CONTACT LENSES, OPHTHALMIC DEVICES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-09-15 | — | — | US | disclosed |
| US-4544572-A | WEAR RESISTANCE, ADHESION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1985-10-01 | — | — | US | disclosed |
| EP-0102847-A1 | Method for coating ophthalmic devices | SIGNET ARMORLITE, INC. (US) | 1984-03-14 | — | — | EP | disclosed |