Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 3/20 | 0.65 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5744744 | 1.00 | OXTR (0.65) | OXTRAVPR1ASMN1; SMN2ACHEBACE1 | |
| SCHEMBL4940289 | 1.00 | OXTR (0.65) | OXTRAVPR1ASMN1; SMN2ACHEBACE1 | |
| SCHEMBL4944228 | 0.89 | OXTR (0.73) | OXTRAVPR1ANPC1PKMRAB9A | |
| SCHEMBL4943936 | 0.87 | SMN1; SMN2 (0.58) | OXTRSMN1; SMN2ACHEBACE1ALDH1A1 | |
| SCHEMBL4939637 | 0.86 | OXTR (0.62) | OXTRAVPR1ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL4944443 | 0.83 | AGTR2 (0.50) | OXTRAVPR1ASMN1; SMN2ACHEBACE1 | |
| SCHEMBL4944440 | 0.83 | AGTR2 (0.50) | OXTRAVPR1ASMN1; SMN2ACHEBACE1 | |
| SCHEMBL7218902 | 0.83 | AGTR2 (0.50) | OXTRAVPR1ASMN1; SMN2ACHEBACE1 | |
| SCHEMBL4939488 | 0.83 | OXTR (0.72) | OXTRAVPR1ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL7080626 | 0.83 | OXTR (0.72) | OXTRAVPR1ASMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268419-B1 | PYRROLIDINE DERIVATIVES USEFUL AS BAX INHIBITORS | APPLIED RESEARCH SYSTEMS (AN) | 2006-06-21 | — | — | EP | disclosed |