Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.40 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23002887 | 1.00 | TSHR (0.56) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL15302389 | 1.00 | TSHR (0.56) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL5746182 | 1.00 | TSHR (0.56) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL6861002 | 0.98 | TSHR (0.53) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL15709964 | 0.95 | TSHR (0.49) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL345559 | 0.89 | THRB (0.49) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL180279 | 0.89 | TSHR (0.65) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL3195852 | 0.89 | TSHR (0.65) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL5958661 | 0.89 | TSHR (0.65) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL5958668 | 0.89 | TSHR (0.65) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1695685-B2 | ONE-PART DENTAL ADHESIVE COMPOSITION | KURARAY NORITAKE DENTAL INC (JP) | 2016-12-28 | — | — | EP | disclosed |
| US-8932060-B2 | Dental treatment method | KURARAY NORITAKE DENTAL INC. (JP) | 2015-01-13 | — | — | US | disclosed |
| US-20130266915-A1 | DENTAL TREATMENT METHOD | KURARAY NORITAKE DENTAL INC. (JP) | 2013-10-10 | — | — | US | disclosed |
| EP-1695685-B1 | ONE-PART DENTAL ADHESIVE COMPOSITION | KURARAY NORITAKE DENTAL INC (JP) | 2012-11-07 | — | — | EP | disclosed |
| EP-1695685-A1 | ONE-PACK TYPE ADHESIVE COMPOSITION FOR DENTAL USE | Kuraray Medical Inc. (JP) | 2006-08-30 | — | — | EP | disclosed |