Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23002887 | 0.98 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5746182 | 0.98 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5744786 | 0.98 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL15302389 | 0.98 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL15709964 | 0.97 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL345559 | 0.90 | THRB (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL40719 | 0.88 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3447223 | 0.87 | BTN3A1 (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL180279 | 0.86 | TSHR (0.65) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5958661 | 0.86 | TSHR (0.65) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11992538-B2 | Polymerizable dental composition based on condensed silanes | VOCO GMBH (DE) | 2024-05-28 | — | — | US | disclosed |
| US-20210052469-A1 | POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES | VOCO GMBH (DE) | 2021-02-25 | — | — | US | disclosed |
| US-8932060-B2 | Dental treatment method | KURARAY NORITAKE DENTAL INC. (JP) | 2015-01-13 | — | — | US | disclosed |
| US-20130266915-A1 | DENTAL TREATMENT METHOD | KURARAY NORITAKE DENTAL INC. (JP) | 2013-10-10 | — | — | US | disclosed |
| US-6790877-B2 | Bonding compositions for dental use | KURARAY CO., LTD. (JP) | 2004-09-14 | — | — | US | disclosed |
| US-20020035169-A1 | Bonding compositions for dental use | KURARAY CO., LTD (JP) | 2002-03-21 | — | — | US | disclosed |
| US-6355704-B1 | BACTERICIDE PRIMERS; BONDING TO TEETH | KURARAY CO., LTD. (JP) | 2002-03-12 | — | — | US | disclosed |
| EP-0980682-A1 | Bonding compositions for dental use | KURARAY CO., LTD. (JP) | 2000-02-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020035169-A1 | Bonding compositions for dental use | PTK2, DEK, POLK | TSHR 4726/4885THRB 3603/4885POLB 39/4885 |
| US-11992538-B2 | Polymerizable dental composition based on condensed silanes | NCAPH, RCC1, NCAPD2 | TSHR 4596/4885THRB 4522/4885POLB 567/4885 |
| US-20210052469-A1 | POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES | NCAPH, RCC1, NCAPD2 | TSHR 4596/4885THRB 4522/4885POLB 567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.