SCHEMBL57452

SCHEMBL57452

C=CC(=O)P(=O)(OC)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.44
ALOX15 P16050 1/20 0.44
POLB P06746 2/20 0.42
PKM P14618 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
LMNA P02545 2/20 0.39
AKT1 P31749 1/20 0.38
CA2 P00918 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
CA4 P22748 1/20 0.38
CA5A P35218 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
USP2 O75604 1/20 0.36
ESR1 P03372 1/20 0.36
TGM2 P21980 2/20 0.36
ALDH1A1 P00352 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
CFTR P13569 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11136167 0.77 POLB (0.47) TSHRPOLBLMNACA2MEN1
SCHEMBL83640 0.75 ALOX15 (0.52) TSHRALOX15PKMSMN1; SMN2LMNA
SCHEMBL18040244 0.74 POLB (0.49) TSHRPOLBLMNAAKT1CA2
SCHEMBL57751 0.73 POLB (0.43) TSHRPOLBPKMSMN1; SMN2LMNA
SCHEMBL56655 0.73 ALDH1A1 (0.44) TSHRPOLBSMN1; SMN2LMNACA2
SCHEMBL14181491 0.71 POLB (0.46) TSHRPOLBPKMLMNACA2
SCHEMBL777461 0.69 ALOX15 (0.50) TSHRALOX15POLBPKMSMN1; SMN2
SCHEMBL10950897 0.69 ALOX15 (0.45) TSHRALOX15PKMSMN1; SMN2AKT1
SCHEMBL19869151 0.69 THRB (0.45) TSHRALOX15POLBPKMSMN1; SMN2
SCHEMBL24033691 0.69 GAA (0.42) TSHRPOLBSMN1; SMN2LMNACA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250051500-A1 RADIATION-CURABLE COMPOSITION MARABU GMBH & CO. KG (DE) 2025-02-13 US claimed
EP-4506424-A1 RADIATION-CURABLE COMPOSITION Marabu GmbH & Co. KG (DE) 2025-02-12 EP claimed
EP-4056658-A1 RADIATION-CURABLE COMPOUND Marabu GmbH & Co. KG (DE) 2022-09-14 EP claimed
US-20250051500-A1 RADIATION-CURABLE COMPOSITION MARABU GMBH & CO. KG (DE) 2025-02-13 US disclosed
EP-4506424-A1 RADIATION-CURABLE COMPOSITION Marabu GmbH & Co. KG (DE) 2025-02-12 EP disclosed
US-12031045-B2 Radiation-curable composition MARABU GMBH & CO. KG (DE) 2024-07-09 US disclosed
US-11945891-B2 Speaker having an adhesive composition DENKA COMPANY LIMITED (JP) 2024-04-02 US disclosed
CN-111315828-B Composition, cured product, optical filter, and method for producing cured product 株式会社艾迪科 2023-09-29 CN disclosed
CN-112154167-B Composition, cured product, optical filter, and method for producing cured product 株式会社艾迪科 2023-08-22 CN disclosed
EP-3591014-B1 LIQUID COMPOSITION FOR INKJET AND INKJET RECORDING METHOD FUJIFILM CORP (JP) 2023-08-16 EP disclosed
US-20220380611-A1 RADIATION-CURABLE COMPOSITION MARABU GMBH & CO. KG (DE) 2022-12-01 US disclosed
EP-1829680-A1 Ink composition, inkjet recording method, printed material, and process for producing lithographic printing plate FUJIFILM Corporation (JP) 2007-09-05 EP disclosed
US-20050185232-A1 Volume hologram recording photosensitive composition and its use NIPPON PAINT CO., LTD. (JP) 2005-08-25 US disclosed
WO-2003068785-A1 MONO- AND BIACYLPHOSPHINE DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 2003-08-21 WO disclosed
US-5698285-A PHOTOCURABLE THREE BOND CO., LTD. (JP) 1997-12-16 US disclosed
US-4707432-A PROTECTIVE COATINGS, IMAGES CIBA-GEIGY CORPORATION (US) 1987-11-17 US disclosed
EP-0007508-B1 ACYLPHOSPHINOXIDE COMPOUNDS, THEIR PREPARATION AND THEIR USE BASF Aktiengesellschaft (DE) 1983-06-01 EP disclosed
US-4324744-A PHOTOINITIATORS BASF AKTIENGESELLSCHAFT (DE) 1982-04-13 US disclosed
US-4265723-A UNSATURATED POLYESTERS OR VINYL ESTERS OF POLYEPOXIDES AND A UV SENSITIZER OF AN ACYL PHOSPHINE OXIDE BASF AKTIENGESELLSCHAFT (DE) 1981-05-05 US disclosed
EP-0007508-A2 Acylphosphinoxide compounds, their preparation and their use BASF Aktiengesellschaft (DE) 1980-02-06 EP disclosed