Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 6/20 | 0.46 |
| ▸ | OXTR | P30559 | 4/20 | 0.46 |
| ▸ | GHSR | Q92847 | 1/20 | 0.44 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14155200 | 0.89 | GHSR (0.45) | AVPR1AOXTRGHSRSLC6A7AVPR2 | |
| SCHEMBL5741557 | 0.87 | SMN1; SMN2 (0.50) | NAMPTGRM5MEN1KMT2AGAA | |
| SCHEMBL5741564 | 0.87 | SMN1; SMN2 (0.50) | NAMPTGRM5MEN1KMT2AGAA | |
| SCHEMBL4944058 | 0.85 | AVPR1A (0.65) | AVPR1AOXTRGHSRSLC6A7AVPR2 | |
| SCHEMBL4944054 | 0.85 | AVPR1A (0.65) | AVPR1AOXTRGHSRSLC6A7AVPR2 | |
| SCHEMBL6017547 | 0.82 | AVPR1A (0.57) | AVPR1AOXTRGHSRSLC6A7AVPR2 | |
| SCHEMBL5481411 | 0.82 | AVPR1A (0.57) | AVPR1AOXTRGHSRSLC6A7AVPR2 | |
| SCHEMBL29396604 | 0.82 | AVPR1A (0.57) | AVPR1AOXTRGHSRSLC6A7AVPR2 | |
| SCHEMBL7083640 | 0.81 | MAPT (0.47) | AVPR1AOXTRGHSRSLC6A7NAMPT | |
| SCHEMBL7086418 | 0.79 | POLB (0.47) | SLC6A7MEN1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268419-B1 | PYRROLIDINE DERIVATIVES USEFUL AS BAX INHIBITORS | APPLIED RESEARCH SYSTEMS (AN) | 2006-06-21 | — | — | EP | claimed |