Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10976389 | 0.85 | BCHE (0.49) | BCHEACHEKIF11ALDH1A1TSHR | |
| SCHEMBL14378211 | 0.80 | BCHE (0.49) | BCHEACHEKIF11ALDH1A1TSHR | |
| SCHEMBL1958962 | 0.79 | KIF11 (0.51) | BCHEACHEKIF11KMT2ACA1 | |
| SCHEMBL4073629 | 0.78 | MMP2 (0.50) | BCHEACHEKIF11ALDH1A1TSHR | |
| SCHEMBL14426927 | 0.76 | BCHE (0.46) | BCHEACHEKIF11ALDH1A1TSHR | |
| SCHEMBL3237305 | 0.75 | KEAP1 (0.46) | BCHEACHECA12CA1CA2 | |
| SCHEMBL514549 | 0.75 | BCHE (0.47) | BCHEACHEKIF11ALDH1A1TSHR | |
| SCHEMBL20499450 | 0.75 | BCHE (0.47) | BCHEACHEKIF11ALDH1A1TSHR | |
| SCHEMBL19857239 | 0.75 | KIF11 (0.54) | BCHEACHEKIF11ALDH1A1TSHR | |
| SCHEMBL514550 | 0.75 | BCHE (0.50) | BCHEACHEKIF11ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1625112-A1 | NOVEL COMPOUNDS FOR TREATMENT OF OBESITY | NOVO NORDISK A/S (DK) | 2006-02-15 | — | — | EP | disclosed |
| WO-2004101505-A1 | NOVEL COMPOUNDS FOR TREATMENT OF OBESITY | NOVO NORDISK A/S (DK) | 2004-11-25 | — | — | WO | disclosed |