Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 8/20 | 0.39 |
| ▸ | CA2 | P00918 | 8/20 | 0.39 |
| ▸ | CA9 | Q16790 | 7/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | CA3 | P07451 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA6 | P23280 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10773280 | 1.00 | THRB (0.44) | THRBTSHRDNM1MEN1HTT | |
| SCHEMBL7053406 | 1.00 | THRB (0.44) | THRBTSHRDNM1MEN1HTT | |
| SCHEMBL5198792 | 1.00 | THRB (0.44) | THRBTSHRDNM1MEN1HTT | |
| SCHEMBL19809309 | 0.97 | DNM1 (0.39) | THRBTSHRDNM1MEN1HTT | |
| SCHEMBL1974322 | 0.95 | THRB (0.40) | THRBTSHRDNM1MEN1HTT | |
| SCHEMBL6303881 | 0.89 | TSHR (0.44) | THRBTSHRDNM1MEN1HTT | |
| SCHEMBL308612 | 0.88 | ADRB2 (0.43) | THRBTSHRDNM1CA1CA2 | |
| SCHEMBL839812 | 0.85 | DNM1 (0.38) | THRBTSHRDNM1MEN1HTT | |
| SCHEMBL839410 | 0.85 | DNM1 (0.38) | THRBTSHRDNM1MEN1HTT | |
| SCHEMBL1607982 | 0.84 | DNM1 (0.35) | THRBTSHRDNM1MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110885427-A | Tin-free catalysis of silane-functional polyurethane crosslinkers | 赢创运营有限公司 | 2020-03-17 | — | — | CN | disclosed |
| CN-106046050-B | Adducts of isocyanatoalkyltrimethoxysilane with flame retardants reactive therewith | 赢创德固赛有限公司 | 2019-12-24 | — | — | CN | disclosed |
| EP-3356444-A1 | ISOCYANATOALKYL ALKOXYSILANE ADDUCTS MODIFIED BY SILICONE RESINS AND THE USE THEREOF | Evonik Degussa GmbH (DE) | 2018-08-08 | — | — | EP | disclosed |
| EP-2552925-A1 | PROCESS FOR PREPARING SILICON-CONTAINING AZODICARBAMIDES | Evonik Degussa GmbH (DE) | 2013-02-06 | — | — | EP | disclosed |
| EP-1637535-A1 | Process for preparing mercaptoorganyl alkoxy silanes | Degussa GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |