Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.38 |
| ▸ | NNMT | P40261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 4/20 | 0.37 |
| ▸ | JAK1 | P23458 | 4/20 | 0.37 |
| ▸ | TYK2 | P29597 | 4/20 | 0.37 |
| ▸ | JAK3 | P52333 | 4/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.35 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5553513 | 0.87 | LCK (0.43) | LCKHPGDSKMT2AFGFR1CHEK2 | |
| SCHEMBL28140566 | 0.85 | TDP1 (0.46) | KMT2AFGFR1SMN1; SMN2PLAUKDM4E | |
| SCHEMBL16289641 | 0.80 | HTT (0.49) | LCKFGFR1KDM4EGLA | |
| SCHEMBL3389355 | 0.73 | ALDH1A1 (0.50) | KMT2AFGFR1KDM4E | |
| SCHEMBL2232014 | 0.72 | ALDH1A1 (0.55) | LCKKMT2AJAK2JAK1TYK2 | |
| SCHEMBL31068033 | 0.72 | ALDH1A1 (0.55) | LCKKMT2AJAK2JAK1TYK2 | |
| SCHEMBL6379955 | 0.71 | TDP1 (0.46) | KMT2AFGFR1SMN1; SMN2KDM4E | |
| SCHEMBL2051696 | 0.71 | EGFR (0.56) | LCKHPGDSKMT2AFGFR1NNMT | |
| SCHEMBL5775183 | 0.71 | FGFR1 (0.40) | LCKKMT2AFGFR1CHEK2NNMT | |
| Hydrochloric Acid SCHEMBL28060868 | 0.71 | MEN1 (0.53) | LCKKMT2AJAK2JAK1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |