SCHEMBL16289641

SCHEMBL16289641

COC(=O)c1ccc2c[c]cnc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.49
ALOX15 P16050 1/20 0.49
KDM4E B2RXH2 5/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
XDH P47989 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
TDP1 Q9NUW8 1/20 0.43
LCK P06239 1/20 0.43
FGFR1 P11362 1/20 0.43
CSNK2A1 P68400 1/20 0.42
PTPN11 Q06124 1/20 0.42
MAPK1 P28482 1/20 0.41
KDM6B O15054 1/20 0.41
KDM5C P41229 1/20 0.41
KDM4C Q9H3R0 1/20 0.41
KDM2A Q9Y2K7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5553754 0.88 HTT (0.60) HTTALOX15KDM4ECA12CA1
SCHEMBL5746232 0.80 LCK (0.43) KDM4ELCKFGFR1GLA
SCHEMBL2671065 0.75 ALOX15 (0.77) HTTALOX15FGFR1ALDH1A1CYP19A1
SCHEMBL29893321 0.75 ALOX15 (0.77) HTTALOX15FGFR1ALDH1A1CYP19A1
SCHEMBL18614408 0.74 CSNK2A1 (0.59) HTTALOX15KDM4ECA12CA1
SCHEMBL30507829 0.74 CSNK2A1 (0.59) HTTALOX15KDM4ECA12CA1
SCHEMBL30204433 0.74 ALOX15 (0.54) HTTALOX15KDM4ECA12CA1
SCHEMBL2899731 0.73 PTPN11 (0.53) HTTALOX15KDM4ECA12CA1
SCHEMBL8890461 0.73 LCK (0.50) HTTALOX15KDM4ECA12CA1
SCHEMBL25255029 0.73 HTT (0.52) HTTALOX15KDM4ECA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 EP disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 US disclosed
CN-104955332-B The method of preventing and treating arthropod insect 住友化学株式会社 2017-03-29 CN disclosed
EP-2952096-A1 METHOD FOR CONTROLLING ARTHROPOD PEST Sumitomo Chemical Company, Limited (JP) 2015-12-09 EP disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 US disclosed
CN-104955332-A Method for controlling arthropod pest SUMITOMO CHEMICAL CO 2015-09-30 CN disclosed
US-20150005348-A1 AMIDE COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-01-01 US disclosed
EP-2813492-A1 AMIDE COMPOUND AND USE THEREOF FOR PEST CONTROL Sumitomo Chemical Co., Ltd (JP) 2014-12-17 EP disclosed
CN-104105694-A Amide compound and use thereof for pest control SUMITOMO CHEMICAL CO 2014-10-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST H1-0, H1-3, H1-2 HTT 1442/4885ALOX15 2577/4885KDM4E 1006/4885
US-20150005348-A1 AMIDE COMPOUND AND USE THEREOF FOR PEST CONTROL RPS8, MT-CO2, ARG1 HTT 4118/4885ALOX15 1859/4885KDM4E 1028/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.