SCHEMBL5746296

SCHEMBL5746296

CNCCCCCC(C)NC

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.46
KISS1R Q969F8 1/20 0.35
SIGMAR1 Q99720 2/20 0.34
ADH1B P00325 1/20 0.34
ADH1C P00326 1/20 0.34
ADH1A P07327 1/20 0.34
ADH4 P08319 1/20 0.34
ADH7 P40394 1/20 0.34
HTR2A P28223 1/20 0.34
HRH1 P35367 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.31
PAOX Q6QHF9 1/20 0.30
CPB2 Q96IY4 1/20 0.30
GRIA1 P42261 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18544608 0.97 EPHX1 (0.42) EPHX1KISS1RSIGMAR1ADH1BADH1C
SCHEMBL19426772 0.97 EPHX1 (0.42) EPHX1KISS1RSIGMAR1ADH1BADH1C
SCHEMBL17319479 0.90
SCHEMBL11510560 0.87 ADH1B (0.41) SIGMAR1ADH1BADH1CADH1AADH4
SCHEMBL24050754 0.83 EPHX1 (0.44) EPHX1KISS1RSIGMAR1ADH1BADH1C
SCHEMBL343562 0.79 CYP2C19 (0.37) EPHX1KISS1RHTR2AHRH1PAOX
SCHEMBL17104333 0.79 EPHX1 (0.50) EPHX1KISS1RSIGMAR1HTR2AHRH1
SCHEMBL22564692 0.79 EPHX1 (0.50) EPHX1KISS1RSIGMAR1HTR2AHRH1
SCHEMBL22682128 0.79 LMNA (0.46) SIGMAR1ADH1BADH1CADH1AADH4
SCHEMBL25122641 0.79 EPHX1 (0.50) EPHX1KISS1RSIGMAR1HTR2AHRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357133-A1 NANOMATERIALS COMPRISING CARBONATES BEAM THERAPEUTICS INC. 2023-11-09 US disclosed
EP-1669305-B1 Storage device for hair coloring agent OREAL (FR) 2013-04-10 EP disclosed
CN-1812881-B A metal-polyamide/polyethylene-metal laminate USINOR 2010-09-22 CN disclosed
CN-1812881-A A metal-polyamide/polyethylene-metal laminate USINOR (FR) 2006-08-02 CN disclosed
EP-1669305-A1 Storage device for hair coloring agent L'OREAL (FR) 2006-06-14 EP disclosed
US-RE35509-E Polyphenylene ether/polyamide blends having improved physical properties GENERAL ELECTRICAL COMPANY (US) 1997-05-13 US disclosed
EP-0260314-B1 POLYPHENYLENE ETHER/POLYAMIDE BLENDS HAVING IMPROVED PHYSICAL PROPERTIES GENERAL ELECTRIC COMPANY (US) 1993-09-01 EP disclosed
EP-0195815-B1 FUNCTIONALIZED POLYPHENYLENE ETHERS AND BLENDS WITH POLYAMIDES GENERAL ELECTRIC COMPANY (US) 1991-12-11 EP disclosed
US-5069818-A CHEMICAL RESISTANCE, IMPACT STRENGTH GENERAL ELECTRIC COMPANY (US) 1991-12-03 US disclosed
EP-0436136-A1 Compatibilized polyphenylene ehter resin/nylon resin blends containing aromatic phosphorous-containing compounds GENERAL ELECTRIC COMPANY (US) 1991-07-10 EP disclosed
US-4822836-A WITH FATTY ACID ADDITIVES; DICARBOXYLIC ACIDS (OR DERIVATIVES) AS COMPATIBILIZERS GENERAL ELECTRIC COMPANY (US) 1989-04-18 US disclosed
EP-0308671-A2 Polyphenylene ether/polyamide blends having improved melt flow characteristics GENERAL ELECTRIC COMPANY (US) 1989-03-29 EP disclosed
EP-0260314-A1 POLYPHENYLENE ETHER/POLYAMIDE BLENDS HAVING IMPROVED PHYSICAL PROPERTIES. GEN ELECTRIC (US) 1988-03-23 EP disclosed
WO-1987005304-A1 POLYPHENYLENE ETHER/POLYAMIDE BLENDS HAVING IMPROVED PHYSICAL PROPERTIES THE GENERAL ELECTRIC COMPANY (US) 1987-09-11 WO disclosed
US-4642358-A POLYAMIDES, POLYESTERS GENERAL ELECTRIC COMPANY (US) 1987-02-10 US disclosed
US-4600741-A ACYL MODIFIED POLYPHENYLENE ETHER AS COMPATIBILIZATION AGENT GENERAL ELECTRIC COMPANY (US) 1986-07-15 US disclosed
WO-1986002086-A1 FUNCTIONALIZED POLYPHENYLENE ETHERS AND BLENDS WITH POLYAMIDES GENERAL ELECTRIC COMPANY (US) 1986-04-10 WO disclosed
US-4315086-A POLYPHENYLENE ETHER, POLYAMIDE, SOLVENT AND IMPACT RESISTANCE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-02-09 US disclosed
EP-0024120-A1 Resin compositions comprising polyphenylene oxide, polyamide and a compound improving the impact resistance SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-02-25 EP disclosed
US-4035436-A METALS, HEAT RESISTANCE TOAGOSEI CHEMICAL INDUSTRY CO., LTD. (JA) 1977-07-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357133-A1 NANOMATERIALS COMPRISING CARBONATES PHOSPHO1, CA13, SGMS2 EPHX1 2426/4885KISS1R 4769/4885SIGMAR1 1046/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.