Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 14/20 | 0.49 |
| ▸ | CNR1 | P21554 | 4/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4189467 | 0.94 | LMNA (0.51) | FAAHCNR1CNR2LMNATSHR | |
| SCHEMBL4180075 | 0.87 | FAAH (0.62) | FAAHCNR1CNR2CYP2C19KCNH2 | |
| SCHEMBL4182411 | 0.79 | LMNA (0.51) | FAAHCNR1CNR2LMNATSHR | |
| SCHEMBL4182413 | 0.79 | LMNA (0.51) | FAAHCNR1CNR2LMNATSHR | |
| SCHEMBL4179776 | 0.78 | FAAH (0.50) | FAAHCNR1CNR2CYP2C19KCNH2 | |
| SCHEMBL4079967 | 0.77 | CNR2 (0.51) | FAAHCNR1CNR2LMNATSHR | |
| SCHEMBL4192823 | 0.77 | FAAH (0.57) | FAAHCNR1CNR2CYP2C19KCNH2 | |
| SCHEMBL4075603 | 0.75 | LMNA (0.52) | FAAHCNR1CNR2CYP2C19KCNH2 | |
| SCHEMBL4075138 | 0.74 | FAAH (0.43) | FAAHCNR1CNR2CYP2C19KCNH2 | |
| SCHEMBL4189090 | 0.73 | FAAH (0.64) | FAAHCNR1CNR2CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006525299-A | — | — | 2006-11-09 | — | — | JP | claimed |
| EP-1618105-A1 | AZETIDINECARBOXAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CB1 RECEPTOR MEDIATED DISORDERS | VERNALIS RESEARCH LIMITED (GB) | 2006-01-25 | — | — | EP | claimed |
| WO-2004096794-A1 | AZETIDINECARBOXAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CB1 RECEPTOR MEDIATED DISORDRS | VERNALIS RESEARCH LIMITED (GB) | 2004-11-11 | — | — | WO | claimed |