SCHEMBL5746492

SCHEMBL5746492

Fc1cc(C(F)(F)F)c(Cl)[c]c1Cl

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31
KIF11 P52732 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2464341 0.77
SCHEMBL8975023 0.69 HTR3E (0.42) CYP11B1CYP11B2KIF11
SCHEMBL15850523 0.68 KIF11 (0.44) CYP11B1CYP11B2KIF11
SCHEMBL750791 0.68 CYP11B1 (0.31) CYP11B1CYP11B2KIF11
SCHEMBL7272204 0.67 NOTUM (0.42) CYP11B1CYP11B2KIF11
SCHEMBL10583388 0.67
SCHEMBL272519 0.65
SCHEMBL10742911 0.65 EPAS1 (0.33) CYP11B1CYP11B2KIF11
SCHEMBL753312 0.65
SCHEMBL15063745 0.65 CYP1A2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1392695-B1 TRIAZOLOPYRIMIDINES BAYER CROPSCIENCE AG (DE) 2006-10-04 EP disclosed