⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL750791 | 0.79 | CYP11B1 (0.31) | — | |
| SCHEMBL1864218 | 0.76 | CA2 (0.31) | — | |
| SCHEMBL1861219 | 0.73 | IDO1 (0.43) | — | |
| SCHEMBL147649 | 0.70 | NOTUM (0.32) | — | |
| SCHEMBL10583388 | 0.68 | — | — | |
| SCHEMBL17529648 | 0.67 | SLC1A5 (0.32) | — | |
| SCHEMBL455005 | 0.67 | NOTUM (0.34) | — | |
| SCHEMBL5746492 | 0.65 | CYP11B1 (0.31) | — | |
| SCHEMBL160262 | 0.65 | P2RX7 (0.36) | — | |
| SCHEMBL3087157 | 0.64 | NOTUM (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3045450-B1 | INTERMEDIATE COMPOUNDS IN PROCESSES FOR PRODUCING PYRIDAZINONE COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2018-02-07 | — | — | EP | disclosed |
| US-9428456-B2 | 1-[m-carboxamido(hetero)aryl-methyl]-heterocyclyl-carboxamide derivatives | ACTELION PHARMACEUTICALS LTD (CH) | 2016-08-30 | — | — | US | disclosed |
| EP-3045450-A1 | INTERMEDIATE COMPOUNDS IN A PROCESS FOR PRODUCING PYRIDAZINONE COMPOUNDS | SUMITOMO CHEMICAL CO., LTD. (JP) | 2016-07-20 | — | — | EP | disclosed |
| EP-2734526-B1 | HETEROCYCLIC AMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2016-04-06 | — | — | EP | disclosed |
| EP-2614053-B1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATES THEREOF | SUMITOMO CHEMICAL CO (JP) | 2016-03-23 | — | — | EP | disclosed |
| US-9221832-B2 | Heterocyclic amide derivatives as P2X7 receptor antagonists | ACTELION PHARMACEUTICALS LTD. (CH) | 2015-12-29 | — | — | US | disclosed |
| US-20150336893-A1 | 1-[m-Carboxamido(hetero)aryl-methyl]-heterocyclyl-carboxamide Derivatives | IDORSIA PHARMACEUTICALS LTD (CH) | 2015-11-26 | — | — | US | disclosed |
| WO-2015173035-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-11-19 | — | — | WO | disclosed |
| EP-2864315-A2 | 1-[M-CARBOXAMIDO(HETERO)ARYL-METHYL]-HETEROCYCLYL-CARBOXAMIDE DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2015-04-29 | — | — | EP | disclosed |
| US-8884010-B2 | Method for producing pyridazinone compounds and intermediate thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-11-11 | — | — | US | disclosed |
| US-20130345199-A1 | 1-[M-CARBOXAMIDO(HETERO)ARYL-METHYL]-PIPERIDINE-4-CARBOXAMIDE DERIVATIVES | ACTELION PHARMACEUTICALS LTD. (CH) | 2013-12-26 | — | — | US | disclosed |
| US-8569301-B2 | 6, 6-dioxo-6-thia-1, 4-diaza-naphthalenes as herbicides | SYNGENTA LIMITED (GB) | 2013-10-29 | — | — | US | disclosed |
| WO-2013153394-A1 | QUINOLONONES WITH ANTIBACTERIAL PROPERTIES | REDX PHARMA LIMITED (GB) | 2013-10-17 | — | — | WO | disclosed |
| EP-2430028-B1 | HERBICIDAL COMPOUNDS | SYNGENTA LTD (GB) | 2013-08-28 | — | — | EP | disclosed |
| US-20130172556-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-07-04 | — | — | US | disclosed |
| WO-2013014587-A1 | HETEROCYCLIC AMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-01-31 | — | — | WO | disclosed |
| US-20120115726-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-10 | — | — | US | disclosed |
| EP-2430028-A1 | HERBICIDAL COMPOUNDS | Syngenta Limited (GB) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010130970-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2010-11-18 | — | — | WO | disclosed |
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |