Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5747365 | 0.90 | SMN1; SMN2 (0.53) | SMN1; SMN2TSHRL3MBTL1MAPK1LMNA | |
| SCHEMBL5746821 | 0.87 | LMNA (0.53) | SMN1; SMN2TSHRL3MBTL1MAPK1LMNA | |
| SCHEMBL5746559 | 0.80 | PPARG (0.51) | PPARGSMN1; SMN2TSHRLMNAHTT | |
| SCHEMBL6846385 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2TSHRL3MBTL1MAPK1 | |
| SCHEMBL6841912 | 0.76 | RAB9A (0.45) | SMN1; SMN2TSHRL3MBTL1MAPK1LMNA | |
| SCHEMBL5745760 | 0.76 | MCL1 (0.46) | SMN1; SMN2TSHRLMNA | |
| SCHEMBL13750042 | 0.75 | POLB (0.54) | SMN1; SMN2 | |
| SCHEMBL13749484 | 0.75 | SMN1; SMN2 (0.52) | SMN1; SMN2TSHRL3MBTL1MAPK1LMNA | |
| SCHEMBL12888411 | 0.75 | HTT (0.50) | SMN1; SMN2TSHRL3MBTL1MAPK1LMNA | |
| SCHEMBL5747025 | 0.75 | PPARG (0.45) | PPARGSMN1; SMN2TSHRLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173427-B1 | HYDROXAMIC ACID DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO (JP) | 2006-04-05 | — | — | EP | disclosed |
| US-6713477-B1 | 1,4-BENZTHIAZINES OR BENZOXAZINES; MATRIX METALLOPROTEINASE INHIBITORS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-03-30 | — | — | US | disclosed |