Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyamine SCHEMBL5794953 | 0.89 | RAB9A (0.43) | RAB9ASMN1; SMN2TSHRL3MBTL1MAPK1 | |
| SCHEMBL6847542 | 0.80 | BMP1 (0.40) | TSHRLMNAHTT | |
| SCHEMBL5747365 | 0.77 | SMN1; SMN2 (0.53) | SMN1; SMN2TSHRL3MBTL1MAPK1LMNA | |
| SCHEMBL5746773 | 0.76 | PPARG (0.52) | SMN1; SMN2TSHRL3MBTL1MAPK1LMNA | |
| SCHEMBL5746821 | 0.75 | LMNA (0.53) | SMN1; SMN2TSHRL3MBTL1MAPK1LMNA | |
| SCHEMBL5745179 | 0.74 | THRB (0.47) | TSHRL3MBTL1THRBLMNAHTT | |
| SCHEMBL5747698 | 0.74 | PPARG (0.45) | SMN1; SMN2THRBLMNAHTT | |
| SCHEMBL6847480 | 0.73 | PPARG (0.54) | SMN1; SMN2TSHRL3MBTL1MAPK1LMNA | |
| SCHEMBL5745760 | 0.70 | MCL1 (0.46) | SMN1; SMN2TSHRTHRBLMNA | |
| SCHEMBL5745464 | 0.70 | GAA (0.41) | SMN1; SMN2TSHRL3MBTL1MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6713477-B1 | 1,4-BENZTHIAZINES OR BENZOXAZINES; MATRIX METALLOPROTEINASE INHIBITORS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-03-30 | — | — | US | disclosed |