Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5747320 | 0.92 | PPARG (0.50) | MCL1PPARGGAAHSD17B3ALDH1A1 | |
| SCHEMBL5798276 | 0.87 | MCL1 (0.50) | MCL1PPARGGAAHSD17B3PDPK1 | |
| SCHEMBL5744163 | 0.87 | MCL1 (0.52) | MCL1PPARGGAAHSD17B3PDPK1 | |
| SCHEMBL5745589 | 0.80 | MCL1 (0.47) | MCL1PPARGGAAHSD17B3PDPK1 | |
| SCHEMBL5796548 | 0.79 | MCL1 (0.53) | MCL1PPARGGAAPDPK1ALDH1A1 | |
| Hydroxyamine SCHEMBL5797278 | 0.79 | MCL1 (0.46) | MCL1PPARGGAAHSD17B3PDPK1 | |
| Hydroxyamine SCHEMBL5793019 | 0.77 | MCL1 (0.51) | MCL1PPARGGAAPDPK1ALDH1A1 | |
| SCHEMBL5747025 | 0.77 | PPARG (0.45) | MCL1PPARGGAAHSD17B3ALDH1A1 | |
| SCHEMBL5745145 | 0.76 | PPARG (0.55) | MCL1PPARGGAAHSD17B3ALDH1A1 | |
| SCHEMBL21783138 | 0.74 | MCL1 (0.67) | MCL1PPARGGAAHSD17B3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173427-B1 | HYDROXAMIC ACID DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO (JP) | 2006-04-05 | — | — | EP | disclosed |
| US-6713477-B1 | 1,4-BENZTHIAZINES OR BENZOXAZINES; MATRIX METALLOPROTEINASE INHIBITORS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-03-30 | — | — | US | disclosed |
| EP-1173427-A1 | HYDROXAMIC ACID DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000063197-A1 | HYDROXAMIC ACID DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-10-26 | — | — | WO | disclosed |