SCHEMBL5746997

SCHEMBL5746997

CC(C)CCCc1ccc(Cl)nc1Cl

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.33
HRH4 Q9H3N8 1/20 0.33
GRIN2D O15399 1/20 0.33
GRIN2A Q12879 1/20 0.33
GRIN2B Q13224 1/20 0.33
GRIN2C Q14957 1/20 0.33
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5747353 0.89 HRH4 (0.37) HRH4
SCHEMBL5746427 0.79 CTRC (0.44)
SCHEMBL31072045 0.79 SLC6A2 (0.51) HRH4
SCHEMBL21767557 0.79 SLC6A2 (0.51) HRH4
SCHEMBL5749103 0.78 KCNH2 (0.41)
SCHEMBL5748047 0.76 KCNH2 (0.44)
SCHEMBL5746988 0.76 KCNH2 (0.44)
SCHEMBL15951054 0.76 SIRT2 (0.39)
SCHEMBL5748559 0.75 ALDH1A1 (0.35)
SCHEMBL15951097 0.74 SIRT2 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060293503-A1 Polyaminopyridines and method for producing same SUMITOMO SEIKA CHEMICALS CO., LTD (JP) 2006-12-28 US disclosed
EP-1669390-A1 POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2006-06-14 EP disclosed