Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | TYR | P14679 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5746988 | 1.00 | KCNH2 (0.44) | KCNH2CYP3A4TYRTP53MAPT | |
| SCHEMBL5749380 | 1.00 | KCNH2 (0.44) | KCNH2CYP3A4TYRTP53MAPT | |
| SCHEMBL5749103 | 0.98 | KCNH2 (0.41) | KCNH2CYP3A4TYRTP53MAPT | |
| SCHEMBL5746427 | 0.92 | CTRC (0.44) | KCNH2CYP3A4TYRTP53MAPT | |
| SCHEMBL5748559 | 0.84 | ALDH1A1 (0.35) | HTTKMT2ACTRCKDM4EALDH1A1 | |
| SCHEMBL21230758 | 0.80 | ALOX5 (0.40) | KCNH2CYP3A4TYRTP53MAPT | |
| SCHEMBL15951097 | 0.79 | SIRT2 (0.35) | TLR8 | |
| SCHEMBL10763935 | 0.77 | TLR8 (0.39) | KCNH2CYP3A4TYRTP53MAPT | |
| SCHEMBL20467095 | 0.77 | ALOX5 (0.41) | KCNH2CYP3A4TYRTP53MAPT | |
| SCHEMBL15951054 | 0.77 | SIRT2 (0.39) | TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |