Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIOK2 | Q9BVS4 | 2/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5777222 | 0.96 | RIOK2 (0.42) | RIOK2MAPK10MAPK9EPHX1RAB9A | |
| SCHEMBL5773999 | 0.96 | RIOK2 (0.42) | RIOK2MAPK10MAPK9EPHX1RAB9A | |
| SCHEMBL5771528 | 0.96 | RIOK2 (0.42) | RIOK2MAPK10MAPK9EPHX1RAB9A | |
| SCHEMBL5770717 | 0.91 | RIOK2 (0.44) | RIOK2MAPK10MAPK9EPHX1RAB9A | |
| SCHEMBL5746412 | 0.86 | TRPV1 (0.39) | RIOK2TRPV1KDM4E | |
| SCHEMBL5749407 | 0.86 | TRPV1 (0.39) | RIOK2TRPV1KDM4E | |
| SCHEMBL5745759 | 0.86 | TRPV1 (0.39) | RIOK2TRPV1KDM4E | |
| SCHEMBL5778696 | 0.86 | RIOK2 (0.45) | RIOK2MAPK10MAPK9RAB9ASMN1; SMN2 | |
| SCHEMBL5750951 | 0.85 | KCNH3 (0.44) | MAPK10RAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL5748767 | 0.85 | KCNH3 (0.44) | MAPK10RAB9ASMN1; SMN2NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |