Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIOK2 | Q9BVS4 | 3/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.38 |
| ▸ | SNRK | Q9NRH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5770717 | 0.92 | RIOK2 (0.44) | RIOK2MAPK10MAPK9IGF1RNR3C2 | |
| SCHEMBL5777222 | 0.90 | RIOK2 (0.42) | RIOK2MAPK10MAPK9IGF1RNR3C2 | |
| SCHEMBL5773999 | 0.90 | RIOK2 (0.42) | RIOK2MAPK10MAPK9IGF1RNR3C2 | |
| SCHEMBL5771528 | 0.90 | RIOK2 (0.42) | RIOK2MAPK10MAPK9IGF1RNR3C2 | |
| SCHEMBL5771765 | 0.89 | RIOK2 (0.56) | RIOK2MAPK10MAPK9IGF1RMAPK8 | |
| SCHEMBL5747136 | 0.86 | RIOK2 (0.46) | RIOK2MAPK10MAPK9IGF1RNR3C2 | |
| SCHEMBL5750225 | 0.84 | RIOK2 (0.38) | RIOK2MAPK10MAPK9IGF1RNR3C2 | |
| SCHEMBL5748107 | 0.83 | NR3C2 (0.46) | MAPK10IGF1RNR3C2MAPK8MEN1 | |
| SCHEMBL5770617 | 0.80 | RIOK2 (0.38) | RIOK2MAPK10NR3C2MEN1KMT2A | |
| SCHEMBL5780372 | 0.79 | MAPK10 (0.41) | RIOK2MAPK10NR3C2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |