Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5748767 | 1.00 | KCNH3 (0.44) | KCNH3NR3C2KDM4EMAPTLMNA | |
| SCHEMBL5749197 | 1.00 | KCNH3 (0.44) | KCNH3NR3C2KDM4EMAPTLMNA | |
| SCHEMBL5746928 | 0.94 | NR3C2 (0.43) | KCNH3NR3C2MAPTLMNASMN1; SMN2 | |
| SCHEMBL5748770 | 0.89 | LMNA (0.42) | KDM4ELMNAHTTSMN1; SMN2TDP1 | |
| SCHEMBL5748107 | 0.88 | NR3C2 (0.46) | NR3C2KDM4EMAPTLMNAHTT | |
| SCHEMBL5750234 | 0.87 | TDP1 (0.52) | LMNAHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL5748565 | 0.86 | ALOX12 (0.45) | NR3C2KDM4EHTTSMN1; SMN2MAPK10 | |
| SCHEMBL5747136 | 0.85 | RIOK2 (0.46) | NR3C2KDM4EMAPTLMNASMN1; SMN2 | |
| SCHEMBL5771528 | 0.84 | RIOK2 (0.42) | NR3C2KDM4EMAPTLMNASMN1; SMN2 | |
| SCHEMBL5773999 | 0.84 | RIOK2 (0.42) | NR3C2KDM4EMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |