Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2251757 | 0.83 | TLR8 (0.42) | MAPTATMGAANPC1MEN1 | |
| SCHEMBL458630 | 0.82 | CYP1A2 (0.38) | CYP1A2CYP2A6KDM4EALDH1A1MAPT | |
| SCHEMBL5748051 | 0.80 | TLR8 (0.42) | KDM4EALDH1A1MAPTGAAUSP2 | |
| SCHEMBL2252320 | 0.80 | TLR8 (0.42) | KDM4EALDH1A1MAPTGAAUSP2 | |
| SCHEMBL2256120 | 0.80 | TLR8 (0.42) | KDM4EALDH1A1MAPTGAAUSP2 | |
| SCHEMBL498622 | 0.76 | ALDH1A1 (0.46) | CYP1A2CYP2A6KDM4EALDH1A1MAPT | |
| SCHEMBL5748318 | 0.76 | MTNR1A (0.33) | KDM4EALDH1A1GAAHTR2A | |
| SCHEMBL5751283 | 0.76 | MTNR1A (0.33) | KDM4EALDH1A1GAAHTR2A | |
| SCHEMBL31158567 | 0.75 | ALDH1A1 (0.44) | CYP1A2CYP2A6KDM4EALDH1A1MAPT | |
| SCHEMBL2701203 | 0.75 | CYP1A2 (0.41) | CYP1A2CYP2A6KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |