Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 5/20 | 0.59 |
| ▸ | MAOB | P27338 | 11/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.54 |
| ▸ | BCHE | P06276 | 2/20 | 0.54 |
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5746335 | 0.99 | XDH (0.58) | XDHMAOBHRH3BCHEACHE | |
| SCHEMBL5748857 | 0.97 | XDH (0.55) | XDHMAOBHRH3BCHEACHE | |
| SCHEMBL5747130 | 0.93 | XDH (0.53) | XDHMAOBHRH3BCHEACHE | |
| SCHEMBL5747833 | 0.92 | XDH (0.52) | XDHMAOBHRH3BCHEACHE | |
| SCHEMBL28675845 | 0.81 | XDH (0.66) | XDHMAOBHRH3BCHEACHE | |
| SCHEMBL5747685 | 0.80 | MAOA (0.45) | XDHKDM4EALDH1A1MAPT | |
| SCHEMBL5747968 | 0.77 | MAOA (0.45) | XDHACHEKDM4EALDH1A1MAPT | |
| SCHEMBL5748784 | 0.76 | XDH (0.58) | XDHMAOBHRH3BCHEACHE | |
| SCHEMBL5749171 | 0.76 | XDH (0.57) | XDHBCHEACHEMAPT | |
| SCHEMBL5747519 | 0.76 | MAOA (0.43) | XDHKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1711463-A2 | AMINO-SUBSTITUTED TRICYCLIC DERIVATIVES AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2006-10-18 | — | — | EP | disclosed |
| WO-2005077899-A2 | AMINO-SUBSTITUTED TRICYCLIC DERIVATIVES AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2005-08-25 | — | — | WO | disclosed |