Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5748220 | 0.81 | LIPG (0.41) | TLR8L3MBTL1TDP1KCNH2 | |
| SCHEMBL5750628 | 0.81 | LIPG (0.41) | TLR8L3MBTL1TDP1KCNH2 | |
| SCHEMBL5749865 | 0.81 | LIPG (0.41) | TLR8L3MBTL1TDP1KCNH2 | |
| SCHEMBL4465618 | 0.76 | HTR1A (0.40) | HTR1ALMNAL3MBTL1KDM4EGAA | |
| SCHEMBL27167448 | 0.72 | SMN1; SMN2 (0.33) | LMNASMN1; SMN2KDM4EMAPTTDP1 | |
| SCHEMBL855198 | 0.72 | PARP1 (0.33) | LMNASMN1; SMN2L3MBTL1KDM4EGAA | |
| SCHEMBL8467497 | 0.72 | METAP2 (0.48) | LMNASMN1; SMN2L3MBTL1KDM4EGAA | |
| SCHEMBL3896844 | 0.72 | NR4A2 (0.43) | TAAR1HTR1ALMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL942952 | 0.71 | HTR1A (0.44) | HTR1ALMNASMN1; SMN2MAPTTDP1 | |
| SCHEMBL5749594 | 0.71 | CCR1 (0.40) | LMNASMN1; SMN2L3MBTL1KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |