SCHEMBL5747937

SCHEMBL5747937

O=C(O)[C@@H]1CC2CCCCC2N1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP2D6 P10635 3/20 0.52
▸ LMNA P02545 2/20 0.52
▸ BLM P54132 2/20 0.52
▸ ALOX15 P16050 2/20 0.52
▸ CYP1A2 P05177 2/20 0.52
▸ CYP2C19 P33261 2/20 0.52
▸ TSHR P16473 1/20 0.52
▸ RAB9A P51151 1/20 0.52
▸ MEN1 O00255 1/20 0.52
▸ THRB P10828 1/20 0.52
▸ PMP22 Q01453 1/20 0.52
▸ KMT2A Q03164 1/20 0.52
▸ CTSC P53634 4/20 0.36
▸ PRMT5 O14744 1/20 0.35
▸ WDR77 Q9BQA1 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ SLC1A2 P43004 2/20 0.33
▸ SLC1A1 P43005 2/20 0.33
▸ SLC1A3 P43003 1/20 0.33
▸ GRIK1 P39086 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8244065 1.00 CYP2D6 (0.52) CYP2D6LMNABLMALOX15CYP1A2
SCHEMBL14605825 1.00 CYP2D6 (0.52) CYP2D6LMNABLMALOX15CYP1A2
SCHEMBL5435908 1.00 CYP2D6 (0.52) CYP2D6LMNABLMALOX15CYP1A2
SCHEMBL5429033 1.00 CYP2D6 (0.52) CYP2D6LMNABLMALOX15CYP1A2
SCHEMBL1414979 1.00 CYP2D6 (0.52) CYP2D6LMNABLMALOX15CYP1A2
SCHEMBL5748972 1.00 CYP2D6 (0.52) CYP2D6LMNABLMALOX15CYP1A2
SCHEMBL3330154 1.00 CYP2D6 (0.52) CYP2D6LMNABLMALOX15CYP1A2
SCHEMBL5747307 1.00 CYP2D6 (0.52) CYP2D6LMNABLMALOX15CYP1A2
SCHEMBL22418410 1.00 CYP2D6 (0.52) CYP2D6LMNABLMALOX15CYP1A2
SCHEMBL14052951 1.00 CYP2D6 (0.52) CYP2D6LMNABLMALOX15CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 689 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070295-A Insect neuropeptide analogs 索拉斯塔生物有限公司 2026-05-19 — — CN claimed
CN-122070296-A Insect neuropeptide analogs 索拉斯塔生物有限公司 2026-05-19 — — CN claimed
US-12630588-B2 Bicyclic peptide ligands specific for CD137 BICYCLETX LIMITED (GB) 2026-05-19 — — US claimed
US-20260098072-A1 METHODS OF STIMULATING APPETITE AND/OR INCREASING BODY WEIGHT USING NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR ANTAGONIST ANALOGS ENDEVICA BIO INC (US) 2026-04-09 — — US claimed
US-12590122-B2 NRP-1 binding inhibitory peptides and uses thereof INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2026-03-31 — — US claimed
US-20260085092-A1 MELANOCORTIN RECEPTOR LIGANDS IPSEN PHARMA SAS (FR) 2026-03-26 — — US claimed
US-20260083865-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) LIGANDS AND USE THEREOF 3B PHARMACEUTICALS GMBH (DE) 2026-03-26 — — US claimed
EP-4702044-A1 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS WITH BIO-DISTRIBUTION MODIFIER 3B Pharmaceuticals GmbH (DE) 2026-03-04 — — EP claimed
US-20260001915-A1 METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST RHYTHM PHARMACEUTICALS INC (US) 2026-01-01 — — US claimed
WO-2025245279-A1 NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR AGONISTS AND USE THEREFORE IN TREATMENT OF ADDICTION AND/OR PAIN ENDEVICA BIO, INC. (US) 2025-11-27 — — WO claimed
EP-1140826-B1 METHOD FOR PRODUCING (2S,4R,9S)-OCTAHYDRO-1H-INDOLE-2-CARBOXYLIC ACID AND INTERMEDIATE PRODUCTS THEREFOR ABBOTT GMBH & CO KG (DE) 2004-05-06 — — EP claimed
EP-0279750-B1 AMINOACID DERIVATIVES AS ANTIHYPERTENSIVES Asahi Breweries, Ltd. (JP) 1993-01-20 — — EP claimed
US-5017567-A Steroid antiinflammatory SCHERING CORPORATION (US) 1991-05-21 — — US claimed
EP-0236307-B1 ANTIHYPERTENSIVE AGENTS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THE PREPARATION OF THE AGENTS AND COMPOSITIONS SCHERING CORPORATION (US) 1991-04-17 — — EP claimed
US-4826816-A Antihypertensive compounds SCHERING CORPORATION (US) 1989-05-02 — — US claimed
EP-0115345-B1 PROCESS FOR THE RESOLUTION OF RACEMIC OPTICALLY ACTIVE BICYCLIC IMINO-ALPHA-CARBOXYLIC ACID ESTERS AND USE OF THE COMPOUNDS OBTAINABLE IN THIS WAY FOR THE SYNTHESIS OF CARBOXYALKYL DIPEPTIDES HOECHST AKTIENGESELLSCHAFT (DE) 1988-01-07 — — EP claimed
US-4668796-A Racemates of optically active bicyclic imino-alpha-carboxylic esters HOECHST AKTIENGESELLSCHAFT (DE) 1987-05-26 — — US claimed
US-4616012-A BENZOTHIADIZINYL AND QUINAZOLINYL DERIVATIVES SCHERING CORPORATION (US) 1986-10-07 — — US claimed
US-4559340-A DIURETICS; GLAUCOMA SCHERING CORPORATION (US) 1985-12-17 — — US claimed
EP-0088350-A1 Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them SCHERING CORPORATION (US) 1983-09-14 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260083865-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) LIGANDS AND USE THEREOF KLK3, FOLH1, PSMA1 CYP2D6 4159/4885LMNA 1421/4885BLM 4494/4885
US-12630588-B2 Bicyclic peptide ligands specific for CD137 PTMS, IL36G, HLA-A CYP2D6 1245/4885LMNA 452/4885BLM 2748/4885
US-20260098072-A1 METHODS OF STIMULATING APPETITE AND/OR INCREASING BODY WEIGHT USING NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR ANTAGONIST ANALOGS MC1R, MC4R, MC5R CYP2D6 3205/4885LMNA 4427/4885BLM 4882/4885
US-20260001915-A1 METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST MC4R, NPY4R, MC3R CYP2D6 3052/4885LMNA 4278/4885BLM 4816/4885
US-12590122-B2 NRP-1 binding inhibitory peptides and uses thereof NRP1, FLT1, KDR CYP2D6 3585/4885LMNA 4134/4885BLM 4831/4885
US-20260085092-A1 MELANOCORTIN RECEPTOR LIGANDS THRB, MC1R, MC5R CYP2D6 779/4885LMNA 1483/4885BLM 4664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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