Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL502776 | 1.00 | LMNA (0.48) | LMNACCR5TAAR1CYP2D6MIF | |
| SCHEMBL169508 | 0.85 | LMNA (0.56) | LMNACCR5TAAR1CYP2D6MIF | |
| Ammonia Solution, Strong SCHEMBL1640901 | 0.82 | LMNA (0.54) | LMNACCR5TAAR1CYP2D6MIF | |
| SCHEMBL1144581 | 0.81 | CCR5 (0.49) | LMNACCR5TAAR1CYP2D6MIF | |
| Methylamine SCHEMBL27931105 | 0.80 | LMNA (0.52) | LMNACCR5TAAR1CYP2D6HTR2A | |
| SCHEMBL14906018 | 0.78 | LMNA (0.50) | LMNACCR5TAAR1CYP2D6MIF | |
| Hypochlorous Acid SCHEMBL11415854 | 0.78 | LMNA (0.56) | LMNACCR5TAAR1CYP2D6HKDC1 | |
| SCHEMBL1144422 | 0.77 | CCR5 (0.46) | LMNACCR5TAAR1CYP2D6MIF | |
| SCHEMBL233438 | 0.76 | LMNA (0.48) | LMNACCR5TAAR1CYP2D6MIF | |
| SCHEMBL5610292 | 0.76 | LMNA (0.48) | LMNACCR5TAAR1CYP2D6MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11804603-B2 | Electrodes for lithium-ion batteries and other | FACTORIAL INC. (US) | 2023-10-31 | — | — | US | disclosed |
| US-20230203212-A1 | COPOLYMERS CONTAINING PENDANT IONOMERIC CARBOSILANE GROUPS | US DEPARTMENT OF ENERGY | 2023-06-29 | — | — | US | disclosed |
| US-20170196862-A2 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2017-07-13 | — | — | US | disclosed |
| CN-103228621-B | Labeling reagent, and method for sequencing and quantifying polypeptide and protein using same | 浦项工科大学校产学协力团 | 2016-06-15 | — | — | CN | disclosed |
| CN-103228621-A | Labeling reagent, and amino acid sequence and protein multiplex quantitative simultaneous analysis method using same | POSTECH ACAD IND FOUND | 2013-07-31 | — | — | CN | disclosed |
| EP-2600853-A1 | COMBINATIONS COMPRISING ATYPICAL ANTIPSYCHOTICS AND TAAR1 AGONISTS | F.HOFFMANN-LA ROCHE AG (CH) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012016879-A1 | COMBINATIONS COMPRISING ATYPICAL ANTIPSYCHOTICS AND TAAR1 AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170196862-A2 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | CFTR, SCNN1B, SLC26A4 | LMNA 3018/4885CCR5 594/4885TAAR1 2181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.