Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11612160 | 0.81 | NOTUM (0.50) | L3MBTL1MAPTPOLBTDP1NOTUM | |
| SCHEMBL14829400 | 0.78 | RAB9A (0.50) | MAPTPOLBNOTUMSMN1; SMN2RAB9A | |
| SCHEMBL3221069 | 0.78 | L3MBTL1 (0.48) | L3MBTL1MAPTPOLBTDP1NOTUM | |
| SCHEMBL3224943 | 0.73 | NOTUM (0.50) | L3MBTL1MAPTPOLBTDP1NOTUM | |
| SCHEMBL3222545 | 0.72 | L3MBTL1 (0.45) | L3MBTL1MAPTPOLBTDP1NOTUM | |
| SCHEMBL4125826 | 0.71 | NOTUM (0.47) | MAPTPOLBNOTUMSMN1; SMN2RAB9A | |
| SCHEMBL3820935 | 0.71 | MME (0.47) | L3MBTL1POLBNOTUMSMN1; SMN2RAB9A | |
| SCHEMBL16826415 | 0.70 | KMO (0.50) | L3MBTL1MAPTPOLBTDP1NOTUM | |
| SCHEMBL13692212 | 0.70 | AHR (0.46) | L3MBTL1MAPTPOLBNOTUMSMN1; SMN2 | |
| SCHEMBL9829861 | 0.70 | L3MBTL1 (0.49) | L3MBTL1MAPTPOLBTDP1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651631-A1 | BICYCLIC IMIDAZOL DERIVATIVES AGAINST FLAVIVIRIDAE | GENELABS TECHNOLOGIES, INC. (US) | 2006-05-03 | — | — | EP | disclosed |
| WO-2005012288-A1 | BICYCLIC IMIDAZOL DERIVATIVES AGAINST FLAVIVIRIDAE | GENELABS TECHNOLOGIES, INC (US) | 2005-02-10 | — | — | WO | disclosed |