Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5749855 | 1.00 | TLR8 (0.48) | TLR8KCNH2LMNATSHRGPBAR1 | |
| SCHEMBL5747355 | 1.00 | TLR8 (0.48) | TLR8KCNH2LMNATSHRGPBAR1 | |
| SCHEMBL17474324 | 0.93 | TLR8 (0.47) | TLR8TSHRGPBAR1 | |
| SCHEMBL9870736 | 0.86 | ALDH1A1 (0.43) | TLR8LMNATSHR | |
| SCHEMBL16720014 | 0.80 | POLB (0.39) | LMNATSHR | |
| SCHEMBL5748142 | 0.79 | NCF1 (0.39) | TLR8 | |
| SCHEMBL2253153 | 0.71 | KCNH2 (0.43) | TLR8KCNH2 | |
| SCHEMBL2514450 | 0.71 | KCNH2 (0.61) | TLR8KCNH2LMNATSHRGPBAR1 | |
| SCHEMBL6115301 | 0.71 | KCNH2 (0.61) | TLR8KCNH2LMNATSHRGPBAR1 | |
| SCHEMBL6114960 | 0.71 | KCNH2 (0.61) | TLR8KCNH2LMNATSHRGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |