Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.80 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.80 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.46 |
| ▸ | DRD1 | P21728 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HRH1 | P35367 | 2/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL229946 | 0.87 | CYP2D6 (0.69) | CYP2D6CYP2C19HDAC1HDAC6HDAC2 | |
| SCHEMBL11701437 | 0.87 | CYP2D6 (0.63) | CYP2D6CYP2C19HDAC1HDAC6HDAC2 | |
| SCHEMBL31539931 | 0.87 | CYP2D6 (0.63) | CYP2D6CYP2C19HDAC1HDAC6HDAC2 | |
| SCHEMBL30143833 | 0.87 | CYP2D6 (0.69) | CYP2D6CYP2C19HDAC1HDAC6HDAC2 | |
| SCHEMBL3469210 | 0.85 | CYP2D6 (0.61) | CYP2D6CYP2C19HDAC1HDAC6HDAC2 | |
| SCHEMBL8507125 | 0.83 | CYP2D6 (0.59) | CYP2D6CYP2C19HDAC1HDAC6HDAC2 | |
| SCHEMBL28366068 | 0.83 | CYP2D6 (0.65) | CYP2D6CYP2C19HDAC1HDAC6HDAC2 | |
| SCHEMBL1968010 | 0.83 | CYP2D6 (0.59) | CYP2D6CYP2C19HDAC1HDAC6HDAC2 | |
| SCHEMBL30142907 | 0.82 | CYP2D6 (0.58) | CYP2D6CYP2C19HDAC1HDAC6HDAC2 | |
| SCHEMBL14720136 | 0.82 | CYP2C19 (0.62) | CYP2D6CYP2C19HDAC1HDAC6HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2075245-B1 | Two-photon probe for real-time monitoring of intracellular calcium ions, method for preparing the probe and method for real-time monitoring of intracellular calcium ions using the probe | UNIV KOREA IND & ACAD COOP (KR) | 2014-12-31 | — | — | EP | disclosed |
| US-8129137-B2 | Two-photon probe for real-time monitoring of intracellular free zinc ions, method for preparing the probe and method for real-time monitoring of intracellular free zinc ions using the probe | KOREA UNIVERSITY INDUSTRIAL & ACADEMIC COLLABORATION FOUNDATION (KR) | 2012-03-06 | — | — | US | disclosed |
| US-8084647-B2 | Two-photon probe for real-time monitoring of intracellular calcium ions, method for preparing the probe and method for real-time monitoring of intracellular calcium ions using the probe | Korea University Industry and Academy Cooperation Foundation (KR) | 2011-12-27 | — | — | US | disclosed |
| EP-2119456-B1 | Two-photon probe for real-time monitoring of intracellular free zinc ions, method for preparing the probe and method for real-time monitoring of intracellular free zinc ions using the probe | UNIV IND & ACAD COLLABORATION (KR) | 2011-07-20 | — | — | EP | disclosed |
| US-20090286275-A1 | Two-photon probe for real-time monitoring of intracellular free zinc ions, method for preparing the probe and method for real-time monitoring of intracellular free zinc ions using the probe | SFC CO., LTD. (KR) | 2009-11-19 | — | — | US | disclosed |
| EP-2119456-A1 | Two-photon probe for real-time monitoring of intracellular free zinc ions, method for preparing the probe and method for real-time monitoring of intracellular free zinc ions using the probe | Korea University Industrial & Academic Collaboration Foundation (KR) | 2009-11-18 | — | — | EP | disclosed |
| EP-2075245-A2 | Two-photon probe for real-time monitoring of intracellular calcium ions, method for preparing the probe and method for real-time monitoring of intracellular calcium ions using the probe | Korea University Industry and Academy Cooperation Foundation (KR) | 2009-07-01 | — | — | EP | disclosed |
| WO-2009031734-A1 | TWO-PHOTON PROBE FOR REAL-TIME MONITORING OF INTRACELLULAR CALCIUM IONS, METHOD FOR PREPARING THE PROBE AND METHOD FOR REAL-TIME MONITORING OF INTRACELLULAR CALCIUM IONS USING THE PROBE | KOREA UNIVERSITY INDUSTRIAL & ACADEMIC COLLABORATION FOUNDATION (KR) | 2009-03-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286275-A1 | Two-photon probe for real-time monitoring of intracellular free zinc ions, method for preparing the probe and method for real-time monitoring of intracellular free zinc ions using the probe | SLC39A3, SLC30A7, SLC39A7 | CYP2D6 2429/4885CYP2C19 3253/4885HDAC1 3013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.