Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | UNG | P13051 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5747368 | 0.86 | RAB9A (0.36) | CYP2A6ALDH1A1RAB9AKDM4EPTGS2 | |
| SCHEMBL5747588 | 0.86 | RAB9A (0.36) | CYP2A6ALDH1A1RAB9AKDM4EPTGS2 | |
| SCHEMBL5748128 | 0.85 | CYP2A6 (0.39) | CYP2A6ALDH1A1RAB9AKDM4EPTGS2 | |
| SCHEMBL7793747 | 0.81 | ALDH1A1 (0.37) | ALDH1A1TSHRTDP1 | |
| SCHEMBL5751120 | 0.77 | KIF11 (0.41) | CYP2A6ALDH1A1RAB9AKDM4EPTGS2 | |
| SCHEMBL18936004 | 0.77 | KDM4E (0.30) | ALDH1A1KDM4E | |
| SCHEMBL5746189 | 0.74 | CYP2A6 (0.39) | CYP2A6ALDH1A1RAB9AKIF11TDP1 | |
| SCHEMBL27681403 | 0.73 | CYP2A6 (0.39) | CYP2A6ALDH1A1RAB9AKDM4EPTGS2 | |
| SCHEMBL294273 | 0.73 | TLR8 (0.38) | ALDH1A1 | |
| SCHEMBL294272 | 0.73 | TLR8 (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |