Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 3/20 | 0.37 |
| ▸ | GUSB | P08236 | 2/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4441470 | 0.84 | CCR1 (0.43) | GUSBERBB2CYP1A2FYNMAOA | |
| SCHEMBL4444202 | 0.84 | CCR1 (0.43) | GUSBERBB2CYP1A2FYNMAOA | |
| SCHEMBL5750151 | 0.83 | CYP1A2 (0.43) | GUSBERBB2CYP1A2FYNMAOA | |
| SCHEMBL31174398 | 0.81 | ALDH1A1 (0.40) | TYMSGUSBERBB2CYP1A2FYN | |
| SCHEMBL5747909 | 0.81 | CCR1 (0.35) | TYMSGUSBCYP1A2CCR1CCR5 | |
| SCHEMBL5749869 | 0.81 | CCR1 (0.35) | TYMSGUSBCYP1A2CCR1CCR5 | |
| Hydrazine SCHEMBL16593264 | 0.81 | GUSB (0.49) | GUSBERBB2CYP1A2FYNMAOA | |
| SCHEMBL5747347 | 0.81 | CYP1A2 (0.41) | GUSBERBB2CYP1A2FYNMAOA | |
| Pyrene SCHEMBL20472222 | 0.80 | ALDH1A1 (0.48) | GUSBERBB2CYP1A2FYNMAOA | |
| SCHEMBL52121 | 0.80 | ALDH1A1 (0.48) | GUSBERBB2CYP1A2FYNMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |