SCHEMBL4444202

SCHEMBL4444202

O=Cc1ccc2ccc3c(C=O)ccc4ccc1c2c43

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 2/20 0.43
CCR5 P51681 1/20 0.43
CCR8 P51685 1/20 0.43
MEN1 O00255 5/20 0.40
KMT2A Q03164 5/20 0.40
LMNA P02545 2/20 0.40
KDM4E B2RXH2 2/20 0.40
PABPC1 P11940 1/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TDP1 Q9NUW8 3/20 0.39
THRB P10828 2/20 0.39
BLM P54132 1/20 0.39
GUSB P08236 2/20 0.37
POLB P06746 2/20 0.35
PTPN1 P18031 2/20 0.35
ALDH1A1 P00352 4/20 0.35
HPGD P15428 2/20 0.35
HSD17B10 Q99714 2/20 0.35
CYP1A2 P05177 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4441470 1.00 CCR1 (0.43) CCR1CCR5CCR8MEN1KMT2A
Pyrene SCHEMBL20472222 0.91 ALDH1A1 (0.48) CCR1CCR5CCR8MEN1KMT2A
SCHEMBL29463321 0.91 ALDH1A1 (0.48) CCR1CCR5CCR8MEN1KMT2A
SCHEMBL52121 0.91 ALDH1A1 (0.48) CCR1CCR5CCR8MEN1KMT2A
SCHEMBL30558901 0.91 ALDH1A1 (0.48) CCR1CCR5CCR8MEN1KMT2A
SCHEMBL25300383 0.89 ALDH1A1 (0.47) CCR1CCR5CCR8MEN1KMT2A
SCHEMBL5749869 0.87 CCR1 (0.35) CCR1CCR5CCR8MEN1KMT2A
Hydrazine SCHEMBL16593264 0.87 GUSB (0.49) CCR1CCR5CCR8MEN1KMT2A
SCHEMBL18605752 0.87 KDM4E (0.43) CCR1CCR5CCR8MEN1KMT2A
SCHEMBL5747909 0.87 CCR1 (0.35) CCR1CCR5CCR8MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119955430-A Conductive adhesive and preparation method and application thereof 中国科学院青岛生物能源与过程研究所 2025-05-09 CN claimed
CN-112080156-B Water-soluble dye containing pyrene and preparation method thereof 华东理工大学 2021-10-15 CN claimed
CN-112080156-A Water-soluble dye containing pyrene and preparation method thereof 华东理工大学 2020-12-15 CN claimed
US-12427506-B1 Method for carbon dioxide fixation using a palladium-doped nitrogen-rich organic framework catalyst KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2025-09-30 US disclosed
CN-119955430-A Conductive adhesive and preparation method and application thereof 中国科学院青岛生物能源与过程研究所 2025-05-09 CN disclosed
CN-117645577-A Circular polarization excimer luminescent molecule, luminescent material, preparation method and application thereof 中国科学院化学研究所 2024-03-05 CN disclosed
US-11538999-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2022-12-27 US disclosed
CN-107540614-B Heterocyclic compound and organic light emitting device including the same 三星显示有限公司 2022-10-14 CN disclosed
EP-3263558-B1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2022-04-13 EP disclosed
CN-112080156-B Water-soluble dye containing pyrene and preparation method thereof 华东理工大学 2021-10-15 CN disclosed
CN-112080156-A Water-soluble dye containing pyrene and preparation method thereof 华东理工大学 2020-12-15 CN disclosed
CN-105377863-A Polycyclic compounds MERCK PATENT GMBH 2016-03-02 CN disclosed
WO-2015000546-A1 POLYCYCLIC COMPOUNDS MERCK PATENT GMBH (DE) 2015-01-08 WO disclosed
WO-2015000546-A1 POLYCYCLIC COMPOUNDS MERCK PATENT GMBH (DE) 2015-01-08 WO disclosed
US-20090179196-A1 Pyrene-Based Organic Compound, Transistor Material and Light-Emitting Transistor Device KYUSHU UNIVERSITY (JP) 2009-07-16 US disclosed
US-20090179196-A1 Pyrene-Based Organic Compound, Transistor Material and Light-Emitting Transistor Device KYUSHU UNIVERSITY (JP) 2009-07-16 US disclosed
US-20090179196-A1 Pyrene-Based Organic Compound, Transistor Material and Light-Emitting Transistor Device KYUSHU UNIVERSITY (JP) 2009-07-16 US disclosed
EP-0964045-B1 Polymeric fluorescent substance and organic electroluminescence device SUMITOMO CHEMICAL CO (JP) 2004-10-06 EP disclosed
US-6403237-B1 POLYMER CONTAINING UNSATURATED AROMATIC MONOMER HEAT RESISTANCE; ORANGE TO RED; TRANSPARENT ANODE OR CATHODE SUMITOMO CHEMICAL CO., LTD. (JP) 2002-06-11 US disclosed
EP-0964045-A1 Polymeric fluorescent substance and organic electroluminescence device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-12-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090179196-A1 Pyrene-Based Organic Compound, Transistor Material and Light-Emitting Transistor Device PPOX, JUP, TARDBP CCR1 3951/4885CCR5 2186/4885CCR8 2331/4885
US-12427506-B1 Method for carbon dioxide fixation using a palladium-doped nitrogen-rich organic framework catalyst POF1B, CYP4F12, ETFB CCR1 1171/4885CCR5 1865/4885CCR8 2517/4885
US-11538999-B2 Heterocyclic compound and organic light-emitting device including the same CCNT1, CYP1A1, CRY1 CCR1 1429/4885CCR5 3117/4885CCR8 2882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.