Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | GUSB | P08236 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5747909 | 1.00 | CCR1 (0.35) | CCR1CCR5CCR8GUSBMEN1 | |
| SCHEMBL4441470 | 0.87 | CCR1 (0.43) | CCR1CCR5CCR8GUSBMEN1 | |
| SCHEMBL4444202 | 0.87 | CCR1 (0.43) | CCR1CCR5CCR8GUSBMEN1 | |
| SCHEMBL5747800 | 0.83 | CYP1A2 (0.43) | GUSBMEN1KMT2ALMNAKDM4E | |
| SCHEMBL5749600 | 0.81 | TYMS (0.37) | CCR1CCR5CCR8GUSBMEN1 | |
| Hydrazine SCHEMBL16593264 | 0.80 | GUSB (0.49) | CCR1CCR5CCR8GUSBMEN1 | |
| SCHEMBL867279 | 0.80 | KEAP1 (0.42) | MEN1KMT2ALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL866016 | 0.80 | KEAP1 (0.42) | MEN1KMT2ALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL29372072 | 0.80 | KEAP1 (0.42) | MEN1KMT2ALMNAKDM4ESMN1; SMN2 | |
| Pyrene SCHEMBL20472222 | 0.79 | ALDH1A1 (0.48) | CCR1CCR5CCR8GUSBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |