Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 8/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 7/20 | 0.48 |
| ▸ | CA12 | O43570 | 5/20 | 0.48 |
| ▸ | CA9 | Q16790 | 5/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18704730 | 1.00 | MEN1 (0.77) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL13694012 | 0.95 | MEN1 (0.84) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL15376152 | 0.90 | MEN1 (0.71) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL12341083 | 0.90 | MEN1 (0.71) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL25501121 | 0.89 | MEN1 (0.79) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL16197656 | 0.87 | MEN1 (0.66) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL1709320 | 0.86 | MEN1 (0.60) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL12481928 | 0.86 | MEN1 (0.60) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL1709276 | 0.86 | MEN1 (0.60) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL9327481 | 0.85 | MEN1 (0.73) | MEN1KMT2AGAATDP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697337-A2 | ORNITHINE DERIVATIVES AS PROSTAGLANDIN-E2-AGONISTS OR ANTAGONISTS | Astellas Pharma Inc. (JP) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005061475-A2 | ORNITHINE DERIVATIVES AS PROSTAGLANDIN E2 AGONISTS OR ANTAGONISTS | ASTELLAS PHARMA INC. (JP) | 2005-07-07 | — | — | WO | disclosed |