Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.84 |
| ▸ | GAA | P10253 | 1/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.84 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 6/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 5/20 | 0.46 |
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | CTSS | P25774 | 4/20 | 0.42 |
| ▸ | CTSK | P43235 | 4/20 | 0.42 |
| ▸ | STK17B | O94768 | 1/20 | 0.41 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18704730 | 0.95 | MEN1 (0.77) | MEN1GAAKMT2ATDP1CA2 | |
| SCHEMBL5749667 | 0.95 | MEN1 (0.77) | MEN1GAAKMT2ATDP1CA2 | |
| SCHEMBL12341083 | 0.92 | MEN1 (0.71) | MEN1GAAKMT2ATDP1CA2 | |
| SCHEMBL15376152 | 0.92 | MEN1 (0.71) | MEN1GAAKMT2ATDP1CA2 | |
| SCHEMBL25090844 | 0.89 | MEN1 (0.88) | MEN1GAAKMT2ATDP1CA2 | |
| SCHEMBL16197656 | 0.85 | MEN1 (0.66) | MEN1GAAKMT2ATDP1CA2 | |
| SCHEMBL14630656 | 0.85 | MEN1 (0.81) | MEN1GAAKMT2ATDP1CA2 | |
| SCHEMBL25501121 | 0.84 | MEN1 (0.79) | MEN1GAAKMT2ATDP1CA2 | |
| SCHEMBL17150407 | 0.83 | MEN1 (0.77) | MEN1GAAKMT2ATDP1CA2 | |
| SCHEMBL4820803 | 0.82 | MEN1 (0.76) | MEN1GAAKMT2ATDP1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3470399-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE VALERIC ACID DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2019-04-17 | — | — | EP | disclosed |
| EP-1763351-B9 | 3-AMINOCYCLOPENTANECARBOXAMIDES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE HOLDINGS CORP (US) | 2017-05-31 | — | — | EP | disclosed |
| US-7585938-B2 | Gamma-secretase inhibitors | MORI HIROSHI | 2009-09-08 | — | — | US | disclosed |