Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | HTR5A | P47898 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28039186 | 0.82 | L3MBTL1 (0.38) | L3MBTL1ALDH1A1MEN1KMT2APARP1 | |
| SCHEMBL5747397 | 0.81 | KCNH2 (0.44) | TLR8KCNH2 | |
| SCHEMBL5749261 | 0.76 | ALDH1A1 (0.35) | ELANEL3MBTL1ALDH1A1HTR1AMEN1 | |
| SCHEMBL643810 | 0.73 | KDM4E (0.54) | L3MBTL1ALDH1A1DAOHTR5ALMNA | |
| SCHEMBL29022899 | 0.73 | BACE1 (0.42) | MEN1KMT2ALMNASMN1; SMN2KDM4E | |
| SCHEMBL4154277 | 0.72 | NR4A2 (0.39) | L3MBTL1ALDH1A1MEN1KMT2APARP1 | |
| SCHEMBL16289274 | 0.72 | METAP2 (0.53) | ALDH1A1KMT2ALMNAKDM4EGAA | |
| SCHEMBL4158158 | 0.72 | SMN1; SMN2 (0.35) | L3MBTL1ALDH1A1MEN1KMT2APARP1 | |
| SCHEMBL5750138 | 0.71 | CYP2A6 (0.37) | L3MBTL1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL16289813 | 0.71 | PARP1 (0.38) | L3MBTL1ALDH1A1TAAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |