Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.34 |
| ▸ | MTOR | P42345 | 5/20 | 0.34 |
| ▸ | BRAF | P15056 | 9/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL575020 | 0.84 | KDM1A (0.37) | BRAFHTR1ADRD2HTR7HTR6 | |
| SCHEMBL574457 | 0.83 | BRAF (0.44) | PIK3CAMTORBRAF | |
| SCHEMBL574795 | 0.82 | BRAF (0.39) | PIK3CAMTORBRAFMEN1KMT2A | |
| SCHEMBL575000 | 0.76 | BRAF (0.34) | PIK3CAMTORBRAF | |
| SCHEMBL15192261 | 0.73 | BRAF (0.46) | PIK3CAMTORBRAF | |
| SCHEMBL574842 | 0.72 | BRAF (0.48) | PIK3CAMTORBRAF | |
| SCHEMBL574829 | 0.70 | BRAF (0.44) | PIK3CAMTORBRAF | |
| SCHEMBL574872 | 0.70 | BRAF (0.47) | PIK3CAMTORBRAF | |
| SCHEMBL28039527 | 0.69 | BRAF (0.34) | BRAFFABP4FABP5 | |
| SCHEMBL575024 | 0.69 | CYP4F2 (0.39) | HTR1ADRD2HTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601185-A1 | DERIVATIVES OF PYRAZOLOPHENYL-BENZENESULFONAMIDE COMPOUNDS AND USE THEREOF AS ANTITUMOR AGENTS | Nerviano Medical Sciences S.r.l. (IT) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012016993-A1 | DERIVATIVES OF PYRAZOLOPHENYL-BENZENESULFONAMIDE COMPOUNDS AND USE THEREOF AS ANTITUMOR AGENTS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2012-02-09 | — | — | WO | disclosed |